Testis-specific serine/threonine-protein kinase 1 (TSSK1B)
Homo sapiens — UniProt Q9BXA7
Data last refreshed: (UniProt release unknown)
Key facts
Testis-specific serine/threonine-protein kinase 1 (TSSK1B) is a protein from Homo sapiens identified by UniProt accession Q9BXA7, 367 residues long. MolForge cross-references it against 8 known binders and 35 disease associations.
- UniProt accession: Q9BXA7; gene symbol TSSK1B.
- Organism: Homo sapiens.
- Length: 367 amino acids.
- Top disease associations (Open Targets): bone density, urate measurement and protein measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Testis-specific serine/threonine-protein kinase 1 |
|---|---|
| UniProt accession | Q9BXA7 |
| Gene | TSSK1B |
| Organism | Homo sapiens |
| Length | 367 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (35)
Diseases linked to this target (Open Targets).
- bone density · score 0.17
- urate measurement · score 0.17
- protein measurement · score 0.09
- body mass index · score 0.08
- brain measurement · score 0.08
- serum gamma-glutamyl transferase measurement · score 0.07
- waist-hip ratio · score 0.06
- electrocardiography · score 0.06
- serum albumin measurement · score 0.05
- neutrophil percentage of leukocytes · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9BXA7-F1 | alphafold | PREDICTED | 80.36 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9BXA7.
Amino-acid sequence (367 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with TSSK1B?
The strongest Open Targets associations for TSSK1B are bone density, urate measurement, protein measurement, body mass index and brain measurement.
How long is the TSSK1B protein?
The Homo sapiens TSSK1B protein (UniProt Q9BXA7) is 367 amino acids long.
Browse: Targets: T · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9BXA7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9BXA7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.