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Sal-like protein 3 (SALL3)

Homo sapiens — UniProt Q9BXA9

Gene: SALL3Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Sal-like protein 3 (SALL3) is a protein from Homo sapiens identified by UniProt accession Q9BXA9, 1300 residues long. MolForge cross-references it against 0 known binders and 66 disease associations.

  • UniProt accession: Q9BXA9; gene symbol SALL3.
  • Organism: Homo sapiens.
  • Length: 1300 amino acids.
  • Top disease associations (Open Targets): body mass index, prostate carcinoma and neurodegenerative disease.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameSal-like protein 3
UniProt accessionQ9BXA9
GeneSALL3
OrganismHomo sapiens
Length1300 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (66)

Diseases linked to this target (Open Targets).

  • body mass index · score 0.48
  • prostate carcinoma · score 0.38
  • neurodegenerative disease · score 0.37
  • mathematical ability · score 0.33
  • systolic blood pressure · score 0.16
  • pack-years measurement · score 0.16
  • forced expiratory volume · score 0.11
  • osteoarthritis · score 0.08
  • digit length ratio · score 0.08
  • head and neck squamous cell carcinoma · score 0.07

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q9BXA9-F1alphafoldPREDICTED49.09—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9BXA9.

Amino-acid sequence (1300 residues)

MSRRKQAKPQ HLKSDEELLP PDGAPEHAAP GEGAEDADSG PESRSGGEET SVCEKCCAEF FKWADFLEHQ RSCTKLPPVL IVHEDAPAPP PEDFPEPSPA SSPSERAESE AAEEAGAEGA EGEARPVEKE AEPMDAEPAG DTRAPRPPPA APAPPTPAYG APSTNVTLEA LLSTKVAVAQ FSQGARAAGG SGAGGGVAAA AVPLILEQLM ALQQQQIHQL QLIEQIRSQV ALMQRPPPRP SLSPAAAPSA PGPAPSQLPG LAALPLSAGA PAAAIAGSGP AAPAAFEGAQ PLSRPESGAS TPGGPAEPSA PAAPSAAPAP AAPAPAPAPQ SAASSQPQSA STPPALAPGS LLGAAPGLPS PLLPQTSASG VIFPNPLVSI AATANALDPL SALMKHRKGK PPNVSVFEPK ASAEDPFFKH KCRFCAKVFG SDSALQIHLR SHTGERPFKC NICGNRFSTK GNLKVHFQRH KEKYPHIQMN PYPVPEYLDN VPTCSGIPYG MSLPPEKPVT TWLDSKPVLP TVPTSVGLQL PPTVPGAHGY ADSPSATPAS RSPQRPSPAS SECASLSPGL NHVESGVSAT AESPQSLLGG PPLTKAEPVS LPCTNARAGD APVGAQASAA PTSVDGAPTS LGSPGLPAVS EQFKAQFPFG GLLDSMQTSE TSKLQQLVEN IDKKMTDPNQ CVICHRVLSC QSALKMHYRT HTGERPFKCK ICGRAFTTKG NLKTHFGVHR AKPPLRVQHS CPICQKKFTN AVVLQQHIRM HMGGQIPNTP LPEGFQDAMD SELAYDDKNA ETLSSYDDDM DENSMEDDAE LKDAATDPAK PLLSYAGSCP PSPPSVISSI AALENQMKMI DSVMSCQQLT GLKSVENGSG ESDRLSNDSS SAVGDLESRS AGSPALSESS SSQALSPAPS NGESFRSKSP GLGAPEEPQE IPLKTERPDS PAAAPGSGGA PGRAGIKEEA PFSLLFLSRE RGKCPSTVCG VCGKPFACKS ALEIHYRSHT KERPFVCALC RRGCSTMGNL KQHLLTHRLK ELPSQLFDPN FALGPSQSTP SLISSAAPTM IKMEVNGHGK AMALGEGPPL PAGVQVPAGP QTVMGPGLAP MLAPPPRRTP KQHNCQSCGK TFSSASALQI HERTHTGEKP FGCTICGRAF TTKGNLKVHM GTHMWNNAPA RRGRRLSVEN PMALLGGDAL KFSEMFQKDL AARAMNVDPS FWNQYAAAIT NGLAMKNNEI SVIQNGGIPQ LPVSLGGSAL PPLGSMASGM DKARTGSSPP IVSLDKASSE TAASRPFTRF IEDNKEIGIN

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with SALL3?

The strongest Open Targets associations for SALL3 are body mass index, prostate carcinoma, neurodegenerative disease, mathematical ability and systolic blood pressure.

How long is the SALL3 protein?

The Homo sapiens SALL3 protein (UniProt Q9BXA9) is 1300 amino acids long.

Browse: Targets: S · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ9BXA9
GeneSALL3
OrganismHomo sapiens
Length1300
Binders0
Diseases66
View on UniProt