Cytosolic 5'-nucleotidase 1A (NT5C1A)
Homo sapiens — UniProt Q9BXI3
Data last refreshed: (UniProt release unknown)
Key facts
Cytosolic 5'-nucleotidase 1A (NT5C1A) is a protein from Homo sapiens identified by UniProt accession Q9BXI3, 368 residues long. MolForge cross-references it against 0 known binders and 61 disease associations.
- UniProt accession: Q9BXI3; gene symbol NT5C1A.
- Organism: Homo sapiens.
- Length: 368 amino acids.
- Top disease associations (Open Targets): cutaneous melanoma, inclusion body myositis and Systemic lupus erythematosus.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Cytosolic 5'-nucleotidase 1A |
|---|---|
| UniProt accession | Q9BXI3 |
| Gene | NT5C1A |
| Organism | Homo sapiens |
| Length | 368 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (61)
Diseases linked to this target (Open Targets).
- cutaneous melanoma · score 0.24
- inclusion body myositis · score 0.10
- Systemic lupus erythematosus · score 0.08
- neoplasm · score 0.07
- heel bone mineral density · score 0.04
- pancreatic neoplasm · score 0.03
- dermatomyositis · score 0.03
- attention deficit hyperactivity disorder · score 0.03
- antisocial behaviour measurement · score 0.03
- substance abuse · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9BXI3-F1 | alphafold | PREDICTED | 86.70 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9BXI3.
Amino-acid sequence (368 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with NT5C1A?
The strongest Open Targets associations for NT5C1A are cutaneous melanoma, inclusion body myositis, Systemic lupus erythematosus, neoplasm and heel bone mineral density.
How long is the NT5C1A protein?
The Homo sapiens NT5C1A protein (UniProt Q9BXI3) is 368 amino acids long.
Browse: Targets: N · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9BXI3 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9BXI3 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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