TBC1 domain family member 10A (TBC1D10A)
Homo sapiens — UniProt Q9BXI6
Data last refreshed: (UniProt release unknown)
Key facts
TBC1 domain family member 10A (TBC1D10A) is a protein from Homo sapiens identified by UniProt accession Q9BXI6, 508 residues long. MolForge cross-references it against 0 known binders and 52 disease associations.
- UniProt accession: Q9BXI6; gene symbol TBC1D10A.
- Organism: Homo sapiens.
- Length: 508 amino acids.
- Top disease associations (Open Targets): BMI-adjusted waist-hip ratio, serum albumin measurement and BMI-adjusted waist circumference.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | TBC1 domain family member 10A |
|---|---|
| UniProt accession | Q9BXI6 |
| Gene | TBC1D10A |
| Organism | Homo sapiens |
| Length | 508 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (52)
Diseases linked to this target (Open Targets).
- BMI-adjusted waist-hip ratio · score 0.29
- serum albumin measurement · score 0.25
- BMI-adjusted waist circumference · score 0.16
- calcium measurement · score 0.16
- platelet count · score 0.14
- waist-hip ratio · score 0.13
- platelet crit · score 0.12
- total cholesterol measurement · score 0.10
- urate measurement · score 0.10
- rheumatoid arthritis · score 0.09
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9BXI6-F1 | alphafold | PREDICTED | 76.50 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9BXI6.
Amino-acid sequence (508 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with TBC1D10A?
The strongest Open Targets associations for TBC1D10A are BMI-adjusted waist-hip ratio, serum albumin measurement, BMI-adjusted waist circumference, calcium measurement and platelet count.
How long is the TBC1D10A protein?
The Homo sapiens TBC1D10A protein (UniProt Q9BXI6) is 508 amino acids long.
Browse: Targets: T · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9BXI6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9BXI6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.