Complement C1q tumor necrosis factor-related protein 6 (C1QTNF6)
Homo sapiens — UniProt Q9BXI9
Data last refreshed: (UniProt release unknown)
Key facts
Complement C1q tumor necrosis factor-related protein 6 (C1QTNF6) is a protein from Homo sapiens identified by UniProt accession Q9BXI9, 278 residues long. MolForge cross-references it against 0 known binders and 208 disease associations.
- UniProt accession: Q9BXI9; gene symbol C1QTNF6.
- Organism: Homo sapiens.
- Length: 278 amino acids.
- Top disease associations (Open Targets): hypothyroidism, type 1 diabetes mellitus and neurodegenerative disease.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Complement C1q tumor necrosis factor-related protein 6 |
|---|---|
| UniProt accession | Q9BXI9 |
| Gene | C1QTNF6 |
| Organism | Homo sapiens |
| Length | 278 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (208)
Diseases linked to this target (Open Targets).
- hypothyroidism · score 0.41
- type 1 diabetes mellitus · score 0.37
- neurodegenerative disease · score 0.36
- autoimmune disease · score 0.35
- Vitiligo · score 0.34
- eosinophil count · score 0.34
- Thyroid preparation use measurement · score 0.33
- thyroid disease · score 0.31
- eosinophil percentage of leukocytes · score 0.30
- Hashimoto's thyroiditis · score 0.28
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9BXI9-F1 | alphafold | PREDICTED | 76.57 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9BXI9.
Amino-acid sequence (278 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with C1QTNF6?
The strongest Open Targets associations for C1QTNF6 are hypothyroidism, type 1 diabetes mellitus, neurodegenerative disease, autoimmune disease and Vitiligo.
How long is the C1QTNF6 protein?
The Homo sapiens C1QTNF6 protein (UniProt Q9BXI9) is 278 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9BXI9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9BXI9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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