Complement C1q tumor necrosis factor-related protein 5 (C1QTNF5)
Homo sapiens — UniProt Q9BXJ0
Data last refreshed: (UniProt release unknown)
Key facts
Complement C1q tumor necrosis factor-related protein 5 (C1QTNF5) is a protein from Homo sapiens identified by UniProt accession Q9BXJ0, 243 residues long. MolForge cross-references it against 0 known binders and 145 disease associations.
- UniProt accession: Q9BXJ0; gene symbol C1QTNF5.
- Organism: Homo sapiens.
- Length: 243 amino acids.
- Top disease associations (Open Targets): late-onset retinal degeneration, Retinal dystrophy and retinal degeneration.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Complement C1q tumor necrosis factor-related protein 5 |
|---|---|
| UniProt accession | Q9BXJ0 |
| Gene | C1QTNF5 |
| Organism | Homo sapiens |
| Length | 243 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (145)
Diseases linked to this target (Open Targets).
- late-onset retinal degeneration · score 0.69
- Retinal dystrophy · score 0.47
- retinal degeneration · score 0.42
- retinitis pigmentosa · score 0.40
- neurodegenerative disease · score 0.26
- isolated microphthalmia 5 · score 0.19
- blood protein measurement · score 0.18
- genetic disorder · score 0.17
- Isolated anophthalmia - microphthalmia · score 0.15
- urate measurement · score 0.10
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9BXJ0-F1 | alphafold | PREDICTED | 79.73 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9BXJ0.
Amino-acid sequence (243 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with C1QTNF5?
The strongest Open Targets associations for C1QTNF5 are late-onset retinal degeneration, Retinal dystrophy, retinal degeneration, retinitis pigmentosa and neurodegenerative disease.
How long is the C1QTNF5 protein?
The Homo sapiens C1QTNF5 protein (UniProt Q9BXJ0) is 243 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9BXJ0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9BXJ0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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