Complement C1q tumor necrosis factor-related protein 1 (C1QTNF1)
Homo sapiens — UniProt Q9BXJ1
Data last refreshed: (UniProt release unknown)
Key facts
Complement C1q tumor necrosis factor-related protein 1 (C1QTNF1) is a protein from Homo sapiens identified by UniProt accession Q9BXJ1, 281 residues long. MolForge cross-references it against 0 known binders and 150 disease associations.
- UniProt accession: Q9BXJ1; gene symbol C1QTNF1.
- Organism: Homo sapiens.
- Length: 281 amino acids.
- Top disease associations (Open Targets): endophthalmitis, type 2 diabetes mellitus and coronary artery disease.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Complement C1q tumor necrosis factor-related protein 1 |
|---|---|
| UniProt accession | Q9BXJ1 |
| Gene | C1QTNF1 |
| Organism | Homo sapiens |
| Length | 281 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (150)
Diseases linked to this target (Open Targets).
- endophthalmitis · score 0.19
- type 2 diabetes mellitus · score 0.11
- coronary artery disease · score 0.10
- neoplasm · score 0.09
- hepatocellular carcinoma · score 0.08
- insulin resistance · score 0.08
- glioblastoma multiforme · score 0.08
- non-alcoholic fatty liver disease · score 0.08
- Sepsis · score 0.07
- myocardial infarction · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9BXJ1-F1 | alphafold | PREDICTED | 74.01 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9BXJ1.
Amino-acid sequence (281 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with C1QTNF1?
The strongest Open Targets associations for C1QTNF1 are endophthalmitis, type 2 diabetes mellitus, coronary artery disease, neoplasm and hepatocellular carcinoma.
How long is the C1QTNF1 protein?
The Homo sapiens C1QTNF1 protein (UniProt Q9BXJ1) is 281 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9BXJ1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9BXJ1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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