Complement C1q tumor necrosis factor-related protein 4 (C1QTNF4)
Homo sapiens — UniProt Q9BXJ3
Data last refreshed: (UniProt release unknown)
Key facts
Complement C1q tumor necrosis factor-related protein 4 (C1QTNF4) is a protein from Homo sapiens identified by UniProt accession Q9BXJ3, 329 residues long. MolForge cross-references it against 0 known binders and 129 disease associations.
- UniProt accession: Q9BXJ3; gene symbol C1QTNF4.
- Organism: Homo sapiens.
- Length: 329 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, body fat percentage and body mass index.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Complement C1q tumor necrosis factor-related protein 4 |
|---|---|
| UniProt accession | Q9BXJ3 |
| Gene | C1QTNF4 |
| Organism | Homo sapiens |
| Length | 329 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (129)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.37
- body fat percentage · score 0.19
- body mass index · score 0.17
- fat body mass · score 0.17
- lean body mass · score 0.16
- high density lipoprotein cholesterol measurement · score 0.14
- aspartate aminotransferase measurement · score 0.14
- platelet count · score 0.12
- forced expiratory volume · score 0.12
- loneliness measurement · score 0.12
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9BXJ3-F1 | alphafold | PREDICTED | 85.59 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9BXJ3.
Amino-acid sequence (329 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with C1QTNF4?
The strongest Open Targets associations for C1QTNF4 are neurodegenerative disease, body fat percentage, body mass index, fat body mass and lean body mass.
How long is the C1QTNF4 protein?
The Homo sapiens C1QTNF4 protein (UniProt Q9BXJ3) is 329 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9BXJ3 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9BXJ3 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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