Complement C1q tumor necrosis factor-related protein 3 (C1QTNF3)
Homo sapiens — UniProt Q9BXJ4
Data last refreshed: (UniProt release unknown)
Key facts
Complement C1q tumor necrosis factor-related protein 3 (C1QTNF3) is a protein from Homo sapiens identified by UniProt accession Q9BXJ4, 246 residues long. MolForge cross-references it against 0 known binders and 193 disease associations.
- UniProt accession: Q9BXJ4; gene symbol C1QTNF3.
- Organism: Homo sapiens.
- Length: 246 amino acids.
- Top disease associations (Open Targets): BMI-adjusted waist-hip ratio, waist-hip ratio and neurodegenerative disease.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Complement C1q tumor necrosis factor-related protein 3 |
|---|---|
| UniProt accession | Q9BXJ4 |
| Gene | C1QTNF3 |
| Organism | Homo sapiens |
| Length | 246 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (193)
Diseases linked to this target (Open Targets).
- BMI-adjusted waist-hip ratio · score 0.31
- waist-hip ratio · score 0.22
- neurodegenerative disease · score 0.18
- blood protein measurement · score 0.11
- type 2 diabetes mellitus · score 0.10
- coronary artery disease · score 0.09
- Duane retraction syndrome · score 0.08
- insulin resistance · score 0.08
- isolated asymptomatic elevation of creatine phosphokinase · score 0.08
- atrial fibrillation · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9BXJ4-F1 | alphafold | PREDICTED | 79.26 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9BXJ4.
Amino-acid sequence (246 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with C1QTNF3?
The strongest Open Targets associations for C1QTNF3 are BMI-adjusted waist-hip ratio, waist-hip ratio, neurodegenerative disease, blood protein measurement and type 2 diabetes mellitus.
How long is the C1QTNF3 protein?
The Homo sapiens C1QTNF3 protein (UniProt Q9BXJ4) is 246 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9BXJ4 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9BXJ4 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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