Complement C1q tumor necrosis factor-related protein 2 (C1QTNF2)
Homo sapiens — UniProt Q9BXJ5
Data last refreshed: (UniProt release unknown)
Key facts
Complement C1q tumor necrosis factor-related protein 2 (C1QTNF2) is a protein from Homo sapiens identified by UniProt accession Q9BXJ5, 285 residues long. MolForge cross-references it against 0 known binders and 83 disease associations.
- UniProt accession: Q9BXJ5; gene symbol C1QTNF2.
- Organism: Homo sapiens.
- Length: 285 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, asthma and allergic rhinitis.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Complement C1q tumor necrosis factor-related protein 2 |
|---|---|
| UniProt accession | Q9BXJ5 |
| Gene | C1QTNF2 |
| Organism | Homo sapiens |
| Length | 285 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (83)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.43
- asthma · score 0.07
- allergic rhinitis · score 0.06
- Eczematoid dermatitis · score 0.06
- eosinophil count · score 0.06
- neonatal intrahepatic cholestasis due to citrin deficiency · score 0.05
- glycogen storage disease VI · score 0.05
- body mass index · score 0.05
- Hyperlipoproteinemia type 1 · score 0.05
- Inhalant adrenergic use measurement · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9BXJ5-F1 | alphafold | PREDICTED | 70.94 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9BXJ5.
Amino-acid sequence (285 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with C1QTNF2?
The strongest Open Targets associations for C1QTNF2 are neurodegenerative disease, asthma, allergic rhinitis, Eczematoid dermatitis and eosinophil count.
How long is the C1QTNF2 protein?
The Homo sapiens C1QTNF2 protein (UniProt Q9BXJ5) is 285 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9BXJ5 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9BXJ5 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.