Transmembrane protein 120A (TMEM120A)
Homo sapiens — UniProt Q9BXJ8
Data last refreshed: (UniProt release unknown)
Key facts
Transmembrane protein 120A (TMEM120A) is a protein from Homo sapiens identified by UniProt accession Q9BXJ8, 343 residues long. MolForge cross-references it against 0 known binders and 72 disease associations.
- UniProt accession: Q9BXJ8; gene symbol TMEM120A.
- Organism: Homo sapiens.
- Length: 343 amino acids.
- Top disease associations (Open Targets): vitamin D measurement, platelet count and urate measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Transmembrane protein 120A |
|---|---|
| UniProt accession | Q9BXJ8 |
| Gene | TMEM120A |
| Organism | Homo sapiens |
| Length | 343 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (72)
Diseases linked to this target (Open Targets).
- vitamin D measurement · score 0.24
- platelet count · score 0.19
- urate measurement · score 0.19
- testosterone measurement · score 0.17
- coffee consumption measurement · score 0.16
- congenital adrenal hyperplasia · score 0.16
- congenital adrenal hyperplasia due to cytochrome P450 oxidoreductase deficiency · score 0.16
- neutrophil count · score 0.16
- mean platelet volume · score 0.16
- coffee consumption · score 0.14
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9BXJ8-F1 | alphafold | PREDICTED | 89.22 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9BXJ8.
Amino-acid sequence (343 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with TMEM120A?
The strongest Open Targets associations for TMEM120A are vitamin D measurement, platelet count, urate measurement, testosterone measurement and coffee consumption measurement.
How long is the TMEM120A protein?
The Homo sapiens TMEM120A protein (UniProt Q9BXJ8) is 343 amino acids long.
Browse: Targets: T · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9BXJ8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9BXJ8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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