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N-alpha-acetyltransferase 15, NatA auxiliary subunit (NAA15)

Homo sapiens — UniProt Q9BXJ9

Gene: NAA15Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

N-alpha-acetyltransferase 15, NatA auxiliary subunit (NAA15) is a protein from Homo sapiens identified by UniProt accession Q9BXJ9, 866 residues long. MolForge cross-references it against 0 known binders and 64 disease associations.

  • UniProt accession: Q9BXJ9; gene symbol NAA15.
  • Organism: Homo sapiens.
  • Length: 866 amino acids.
  • Top disease associations (Open Targets): intellectual disability, autosomal dominant 50, genetic disorder and Neurodevelopmental disorder.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameN-alpha-acetyltransferase 15, NatA auxiliary subunit
UniProt accessionQ9BXJ9
GeneNAA15
OrganismHomo sapiens
Length866 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (64)

Diseases linked to this target (Open Targets).

  • intellectual disability, autosomal dominant 50 · score 0.75
  • genetic disorder · score 0.53
  • Neurodevelopmental disorder · score 0.46
  • Intellectual disability · score 0.45
  • neurodegenerative disease · score 0.45
  • autism · score 0.40
  • syndromic intellectual disability · score 0.40
  • complex neurodevelopmental disorder · score 0.37
  • FEV/FVC ratio · score 0.35
  • Global developmental delay · score 0.34

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q9BXJ9-F1alphafoldPREDICTED89.39—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9BXJ9.

Amino-acid sequence (866 residues)

MPAVSLPPKE NALFKRILRC YEHKQYRNGL KFCKQILSNP KFAEHGETLA MKGLTLNCLG KKEEAYELVR RGLRNDLKSH VCWHVYGLLQ RSDKKYDEAI KCYRNALKWD KDNLQILRDL SLLQIQMRDL EGYRETRYQL LQLRPAQRAS WIGYAIAYHL LEDYEMAAKI LEEFRKTQQT SPDKVDYEYS ELLLYQNQVL REAGLYREAL EHLCTYEKQI CDKLAVEETK GELLLQLCRL EDAADVYRGL QERNPENWAY YKGLEKALKP ANMLERLKIY EEAWTKYPRG LVPRRLPLNF LSGEKFKECL DKFLRMNFSK GCPPVFNTLR SLYKDKEKVA IIEELVVGYE TSLKSCRLFN PNDDGKEEPP TTLLWVQYYL AQHYDKIGQP SIALEYINTA IESTPTLIEL FLVKAKIYKH AGNIKEAARW MDEAQALDTA DRFINSKCAK YMLKANLIKE AEEMCSKFTR EGTSAVENLN EMQCMWFQTE CAQAYKAMNK FGEALKKCHE IERHFIEITD DQFDFHTYCM RKITLRSYVD LLKLEDVLRQ HPFYFKAARI AIEIYLKLHD NPLTDENKEH EADTANMSDK ELKKLRNKQR RAQKKAQIEE EKKNAEKEKQ QRNQKKKKDD DDEEIGGPKE ELIPEKLAKV ETPLEEAIKF LTPLKNLVKN KIETHLFAFE IYFRKEKFLL MLQSVKRAFA IDSSHPWLHE CMIRLFNTAV CESKDLSDTV RTVLKQEMNR LFGATNPKNF NETFLKRNSD SLPHRLSAAK MVYYLDPSSQ KRAIELATTL DESLTNRNLQ TCMEVLEALY DGSLGDCKEA AEIYRANCHK LFPYALAFMP PGYEEDMKIT VNGDSSAEAE ELANEI

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with NAA15?

The strongest Open Targets associations for NAA15 are intellectual disability, autosomal dominant 50, genetic disorder, Neurodevelopmental disorder, Intellectual disability and neurodegenerative disease.

How long is the NAA15 protein?

The Homo sapiens NAA15 protein (UniProt Q9BXJ9) is 866 amino acids long.

Browse: Targets: N · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ9BXJ9
GeneNAA15
OrganismHomo sapiens
Length866
Binders0
Diseases64
View on UniProt