Krueppel-like factor 16 (KLF16)
Homo sapiens — UniProt Q9BXK1
Data last refreshed: (UniProt release unknown)
Key facts
Krueppel-like factor 16 (KLF16) is a protein from Homo sapiens identified by UniProt accession Q9BXK1, 252 residues long. MolForge cross-references it against 0 known binders and 93 disease associations.
- UniProt accession: Q9BXK1; gene symbol KLF16.
- Organism: Homo sapiens.
- Length: 252 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, mean corpuscular volume and reticulocyte measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Krueppel-like factor 16 |
|---|---|
| UniProt accession | Q9BXK1 |
| Gene | KLF16 |
| Organism | Homo sapiens |
| Length | 252 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (93)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.55
- mean corpuscular volume · score 0.30
- reticulocyte measurement · score 0.28
- mean corpuscular hemoglobin · score 0.26
- erythrocyte count · score 0.24
- red blood cell density measurement · score 0.23
- reticulocyte count · score 0.22
- mean reticulocyte volume · score 0.22
- mean corpuscular hemoglobin concentration · score 0.21
- FEV/FVC ratio · score 0.20
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9BXK1-F1 | alphafold | PREDICTED | 60.44 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9BXK1.
Amino-acid sequence (252 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with KLF16?
The strongest Open Targets associations for KLF16 are neurodegenerative disease, mean corpuscular volume, reticulocyte measurement, mean corpuscular hemoglobin and erythrocyte count.
How long is the KLF16 protein?
The Homo sapiens KLF16 protein (UniProt Q9BXK1) is 252 amino acids long.
Browse: Targets: K · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9BXK1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9BXK1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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