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Bcl-2-like protein 13 (BCL2L13)

Homo sapiens — UniProt Q9BXK5

Gene: BCL2L13Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Bcl-2-like protein 13 (BCL2L13) is a protein from Homo sapiens identified by UniProt accession Q9BXK5, 485 residues long. MolForge cross-references it against 0 known binders and 63 disease associations.

  • UniProt accession: Q9BXK5; gene symbol BCL2L13.
  • Organism: Homo sapiens.
  • Length: 485 amino acids.
  • Top disease associations (Open Targets): eosinophil count, neutrophil count and leukocyte count.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameBcl-2-like protein 13
UniProt accessionQ9BXK5
GeneBCL2L13
OrganismHomo sapiens
Length485 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (63)

Diseases linked to this target (Open Targets).

  • eosinophil count · score 0.35
  • neutrophil count · score 0.34
  • leukocyte count · score 0.31
  • hemoglobin measurement · score 0.31
  • serum alanine aminotransferase measurement · score 0.31
  • lymphocyte percentage of leukocytes · score 0.29
  • neutrophil percentage of leukocytes · score 0.29
  • neurodegenerative disease · score 0.29
  • erythrocyte count · score 0.29
  • hematocrit · score 0.28

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q9BXK5-F1alphafoldPREDICTED64.51—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9BXK5.

Amino-acid sequence (485 residues)

MASSSTVPLG FHYETKYVVL SYLGLLSQEK LQEQHLSSPQ GVQLDIASQS LDQEILLKVK TEIEEELKSL DKEISEAFTS TGFDRHTSPV FSPANPESSM EDCLAHLGEK VSQELKEPLH KALQMLLSQP VTYQAFRECT LETTVHASGW NKILVPLVLL RQMLLELTRR GQEPLSALLQ FGVTYLEDYS AEYIIQQGGW GTVFSLESEE EEYPGITAED SNDIYILPSD NSGQVSPPES PTVTTSWQSE SLPVSLSASQ SWHTESLPVS LGPESWQQIA MDPEEVKSLD SNGAGEKSEN NSSNSDIVHV EKEEVPEGME EAAVASVVLP ARELQEALPE APAPLLPHIT ATSLLGTREP DTEVITVEKS SPATSLFVEL DEEEVKAATT EPTEVEEVVP ALEPTETLLS EKEINAREES LVEELSPASE KKPVPPSEGK SRLSPAGEMK PMPLSEGKSI LLFGGAAAVA ILAVAIGVAL ALRKK

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with BCL2L13?

The strongest Open Targets associations for BCL2L13 are eosinophil count, neutrophil count, leukocyte count, hemoglobin measurement and serum alanine aminotransferase measurement.

How long is the BCL2L13 protein?

The Homo sapiens BCL2L13 protein (UniProt Q9BXK5) is 485 amino acids long.

Browse: Targets: B · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ9BXK5
GeneBCL2L13
OrganismHomo sapiens
Length485
Binders0
Diseases63
View on UniProt