Asporin (ASPN)
Homo sapiens — UniProt Q9BXN1
Data last refreshed: (UniProt release unknown)
Key facts
Asporin (ASPN) is a protein from Homo sapiens identified by UniProt accession Q9BXN1, 380 residues long. MolForge cross-references it against 0 known binders and 197 disease associations.
- UniProt accession: Q9BXN1; gene symbol ASPN.
- Organism: Homo sapiens.
- Length: 380 amino acids.
- Top disease associations (Open Targets): lumbar disc degeneration, body height and osteoarthritis.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Asporin |
|---|---|
| UniProt accession | Q9BXN1 |
| Gene | ASPN |
| Organism | Homo sapiens |
| Length | 380 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (197)
Diseases linked to this target (Open Targets).
- lumbar disc degeneration · score 0.38
- body height · score 0.33
- osteoarthritis · score 0.19
- creatinine measurement · score 0.12
- neoplasm · score 0.11
- lean body mass · score 0.11
- sitting height measurement · score 0.10
- cancer · score 0.09
- gonorrhea · score 0.08
- glioblastoma multiforme · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9BXN1-F1 | alphafold | PREDICTED | 85.87 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9BXN1.
Amino-acid sequence (380 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ASPN?
The strongest Open Targets associations for ASPN are lumbar disc degeneration, body height, osteoarthritis, creatinine measurement and neoplasm.
How long is the ASPN protein?
The Homo sapiens ASPN protein (UniProt Q9BXN1) is 380 amino acids long.
Browse: Targets: A · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9BXN1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9BXN1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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