C-type lectin domain family 7 member A (CLEC7A)
Homo sapiens — UniProt Q9BXN2
Data last refreshed: (UniProt release unknown)
Key facts
C-type lectin domain family 7 member A (CLEC7A) is a protein from Homo sapiens identified by UniProt accession Q9BXN2, 247 residues long. MolForge cross-references it against 0 known binders and 318 disease associations.
- UniProt accession: Q9BXN2; gene symbol CLEC7A.
- Organism: Homo sapiens.
- Length: 247 amino acids.
- Top disease associations (Open Targets): Chronic mucocutaneous candidosis, candidiasis, familial, 4 and chronic mucocutaneous candidiasis.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | C-type lectin domain family 7 member A |
|---|---|
| UniProt accession | Q9BXN2 |
| Gene | CLEC7A |
| Organism | Homo sapiens |
| Length | 247 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (318)
Diseases linked to this target (Open Targets).
- Chronic mucocutaneous candidosis · score 0.41
- candidiasis, familial, 4 · score 0.38
- chronic mucocutaneous candidiasis · score 0.37
- inflammatory bowel disease · score 0.15
- neoplasm · score 0.11
- infection · score 0.11
- infect · score 0.11
- colitis · score 0.08
- self reported educational attainment · score 0.08
- Rheumatoid arthritis · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9BXN2-F1 | alphafold | PREDICTED | 77.56 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9BXN2.
Amino-acid sequence (247 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CLEC7A?
The strongest Open Targets associations for CLEC7A are Chronic mucocutaneous candidosis, candidiasis, familial, 4, chronic mucocutaneous candidiasis, inflammatory bowel disease and neoplasm.
How long is the CLEC7A protein?
The Homo sapiens CLEC7A protein (UniProt Q9BXN2) is 247 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9BXN2 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9BXN2 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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