Isopentenyl-diphosphate delta-isomerase 2 (IDI2)
Homo sapiens — UniProt Q9BXS1
Data last refreshed: (UniProt release unknown)
Key facts
Isopentenyl-diphosphate delta-isomerase 2 (IDI2) is a protein from Homo sapiens identified by UniProt accession Q9BXS1, 227 residues long. MolForge cross-references it against 0 known binders and 25 disease associations.
- UniProt accession: Q9BXS1; gene symbol IDI2.
- Organism: Homo sapiens.
- Length: 227 amino acids.
- Top disease associations (Open Targets): creatinine measurement, erythrocyte count and glomerular filtration rate.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Isopentenyl-diphosphate delta-isomerase 2 |
|---|---|
| UniProt accession | Q9BXS1 |
| Gene | IDI2 |
| Organism | Homo sapiens |
| Length | 227 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (25)
Diseases linked to this target (Open Targets).
- creatinine measurement · score 0.39
- erythrocyte count · score 0.36
- glomerular filtration rate · score 0.36
- serum urea measurement · score 0.34
- cystatin C measurement · score 0.34
- neurodegenerative disease · score 0.18
- red blood cell density measurement · score 0.14
- neurofibrillary tangles measurement · score 0.14
- testosterone measurement · score 0.11
- chronic kidney disease · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9BXS1-F1 | alphafold | PREDICTED | 95.87 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9BXS1.
Amino-acid sequence (227 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with IDI2?
The strongest Open Targets associations for IDI2 are creatinine measurement, erythrocyte count, glomerular filtration rate, serum urea measurement and cystatin C measurement.
How long is the IDI2 protein?
The Homo sapiens IDI2 protein (UniProt Q9BXS1) is 227 amino acids long.
Browse: Targets: I · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9BXS1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9BXS1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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