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Solute carrier family 26 member 6 (SLC26A6)

Homo sapiens — UniProt Q9BXS9

Gene: SLC26A6Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Solute carrier family 26 member 6 (SLC26A6) is a protein from Homo sapiens identified by UniProt accession Q9BXS9, 759 residues long. MolForge cross-references it against 0 known binders and 108 disease associations.

  • UniProt accession: Q9BXS9; gene symbol SLC26A6.
  • Organism: Homo sapiens.
  • Length: 759 amino acids.
  • Top disease associations (Open Targets): cutaneous melanoma, self reported educational attainment and hepatocyte growth factor-like protein measurement.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameSolute carrier family 26 member 6
UniProt accessionQ9BXS9
GeneSLC26A6
OrganismHomo sapiens
Length759 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (108)

Diseases linked to this target (Open Targets).

  • cutaneous melanoma · score 0.12
  • self reported educational attainment · score 0.12
  • hepatocyte growth factor-like protein measurement · score 0.11
  • anorexia nervosa · score 0.11
  • intelligence · score 0.10
  • unipolar depression · score 0.08
  • hepatocellular carcinoma · score 0.08
  • nephrotic syndrome · score 0.07
  • familial idiopathic steroid-resistant nephrotic syndrome · score 0.06
  • reticulocyte count · score 0.06

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q9BXS9-F1alphafoldPREDICTED82.16—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9BXS9.

Amino-acid sequence (759 residues)

MGLADASGPR DTQALLSATQ AMDLRRRDYH MERPLLNQEH LEELGRWGSA PRTHQWRTWL QCSRARAYAL LLQHLPVLVW LPRYPVRDWL LGDLLSGLSV AIMQLPQGLA YALLAGLPPV FGLYSSFYPV FIYFLFGTSR HISVGTFAVM SVMVGSVTES LAPQALNDSM INETARDAAR VQVASTLSVL VGLFQVGLGL IHFGFVVTYL SEPLVRGYTT AAAVQVFVSQ LKYVFGLHLS SHSGPLSLIY TVLEVCWKLP QSKVGTVVTA AVAGVVLVVV KLLNDKLQQQ LPMPIPGELL TLIGATGISY GMGLKHRFEV DVVGNIPAGL VPPVAPNTQL FSKLVGSAFT IAVVGFAIAI SLGKIFALRH GYRVDSNQEL VALGLSNLIG GIFQCFPVSC SMSRSLVQES TGGNSQVAGA ISSLFILLII VKLGELFHDL PKAVLAAIII VNLKGMLRQL SDMRSLWKAN RADLLIWLVT FTATILLNLD LGLVVAVIFS LLLVVVRTQM PHYSVLGQVP DTDIYRDVAE YSEAKEVRGV KVFRSSATVY FANAEFYSDA LKQRCGVDVD FLISQKKKLL KKQEQLKLKQ LQKEEKLRKQ AASPKGASVS INVNTSLEDM RSNNVEDCKM MQVSSGDKME DATANGQEDS KAPDGSTLKA LGLPQPDFHS LILDLGALSF VDTVCLKSLK NIFHDFREIE VEVYMAACHS PVVSQLEAGH FFDASITKKH LFASVHDAVT FALQHPRPVP DSPVSVTRL

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with SLC26A6?

The strongest Open Targets associations for SLC26A6 are cutaneous melanoma, self reported educational attainment, hepatocyte growth factor-like protein measurement, anorexia nervosa and intelligence.

How long is the SLC26A6 protein?

The Homo sapiens SLC26A6 protein (UniProt Q9BXS9) is 759 amino acids long.

Browse: Targets: S · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ9BXS9
GeneSLC26A6
OrganismHomo sapiens
Length759
Binders0
Diseases108
View on UniProt