Testis-expressed protein 12 (TEX12)
Homo sapiens — UniProt Q9BXU0
Data last refreshed: (UniProt release unknown)
Key facts
Testis-expressed protein 12 (TEX12) is a protein from Homo sapiens identified by UniProt accession Q9BXU0, 123 residues long. MolForge cross-references it against 0 known binders and 122 disease associations.
- UniProt accession: Q9BXU0; gene symbol TEX12.
- Organism: Homo sapiens.
- Length: 123 amino acids.
- Top disease associations (Open Targets): interleukin 18 measurement, squamous cell lung carcinoma and heel bone mineral density.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Testis-expressed protein 12 |
|---|---|
| UniProt accession | Q9BXU0 |
| Gene | TEX12 |
| Organism | Homo sapiens |
| Length | 123 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (122)
Diseases linked to this target (Open Targets).
- interleukin 18 measurement · score 0.12
- squamous cell lung carcinoma · score 0.10
- heel bone mineral density · score 0.10
- bone quantitative ultrasound measurement · score 0.10
- memory impairment · score 0.09
- alcohol drinking · score 0.09
- bone density · score 0.08
- cancer · score 0.08
- azoospermia · score 0.08
- male infertility with teratozoospermia due to single gene mutation · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9BXU0-F1 | alphafold | PREDICTED | 79.73 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9BXU0.
Amino-acid sequence (123 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with TEX12?
The strongest Open Targets associations for TEX12 are interleukin 18 measurement, squamous cell lung carcinoma, heel bone mineral density, bone quantitative ultrasound measurement and memory impairment.
How long is the TEX12 protein?
The Homo sapiens TEX12 protein (UniProt Q9BXU0) is 123 amino acids long.
Browse: Targets: T · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9BXU0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9BXU0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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