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Serine/threonine-protein kinase 31 (STK31)

Homo sapiens — UniProt Q9BXU1

Gene: STK31Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Serine/threonine-protein kinase 31 (STK31) is a protein from Homo sapiens identified by UniProt accession Q9BXU1, 1019 residues long. MolForge cross-references it against 0 known binders and 41 disease associations.

  • UniProt accession: Q9BXU1; gene symbol STK31.
  • Organism: Homo sapiens.
  • Length: 1019 amino acids.
  • Top disease associations (Open Targets): mathematical ability, schizophrenia and type 2 diabetes mellitus.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameSerine/threonine-protein kinase 31
UniProt accessionQ9BXU1
GeneSTK31
OrganismHomo sapiens
Length1019 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (41)

Diseases linked to this target (Open Targets).

  • mathematical ability · score 0.26
  • schizophrenia · score 0.24
  • type 2 diabetes mellitus · score 0.23
  • neurodegenerative disease · score 0.20
  • chronotype measurement · score 0.17
  • vital capacity · score 0.15
  • body height · score 0.13
  • calf circumference measurement · score 0.07
  • pachyonychia congenita · score 0.07
  • PHF-tau measurement · score 0.06

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q9BXU1-F1alphafoldPREDICTED76.66—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9BXU1.

Amino-acid sequence (1019 residues)

MWVQGHSSRA SATESVSFSG IVQMDEDTHY DKVEDVVGSH IEDAVTFWAQ SINRNKDIMK IGCSLSEVCP QASSVLGNLD PNKIYGGLFS EDQCWYRCKV LKIISVEKCL VRYIDYGNTE ILNRSDIVEI PLELQFSSVA KKYKLWGLHI PSDQEVTQFD QGTTFLGSLI FEKEIKMRIK ATSEDGTVIA QAEYGSVDIG EEVLKKGFAE KCRLASRTDI CEEKKLDPGQ LVLRNLKSPI PLWGHRSNQS TFSRPKGHLS EKMTLDLKDE NDAGNLITFP KESLAVGDFN LGSNVSLEKI KQDQKLIEEN EKLKTEKDAL LESYKALELK VEQIAQELQQ EKAAAVDLTN HLEYTLKTYI DTRMKNLAAK MEILKEMRHV DISVRFGKDL SDAIQVLDEG CFTTPASLNG LEIIWAEYSL AQENIKTCEY VSEGNILIAQ RNEMQQKLYM SVEDFILEVD ESSLNKRLKT LQDLSVSLEA VYGQAKEGAN SDEILKKFYD WKCDKREEFT SVRSETDASL HRLVAWFQRT LKVFDLSVEG SLISEDAMDN IDEILEKTES SVCKELEIAL VDQGDADKEI ISNTYSQVLQ KIHSEERLIA TVQAKYKDSI EFKKQLIEYL NKSPSVDHLL SIKKTLKSLK ALLRWKLVEK SNLEESDDPD GSQIEKIKEE ITQLRNNVFQ EIYHEREEYE MLTSLAQKWF PELPLLHPEI GLLKYMNSGG LLTMSLERDL LDAEPMKELS SKRPLVRSEV NGQIILLKGY SVDVDTEAKV IERAATYHRA WREAEGDSGL LPLIFLFLCK SDPMAYLMVP YYPRANLNAV QANMPLNSEE TLKVMKGVAQ GLHTLHKADI IHGSLHQNNV FALNREQGIV GDFDFTKSVS QRASVNMMVG DLSLMSPELK MGKPASPGSD LYAYGCLLLW LSVQNQEFEI NKDGIPKVDQ FHLDDKVKSL LCSLICYRSS MTAEQVLNAE CFLMPKEQSV PNPEKDTEYT LYKKEEEIKT ENLDKCMEKT RNGEANFDC

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with STK31?

The strongest Open Targets associations for STK31 are mathematical ability, schizophrenia, type 2 diabetes mellitus, neurodegenerative disease and chronotype measurement.

How long is the STK31 protein?

The Homo sapiens STK31 protein (UniProt Q9BXU1) is 1019 amino acids long.

Browse: Targets: S · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ9BXU1
GeneSTK31
OrganismHomo sapiens
Length1019
Binders0
Diseases41
View on UniProt