Ubiquitin carboxyl-terminal hydrolase 26 (USP26)
Homo sapiens — UniProt Q9BXU7
Data last refreshed: (UniProt release unknown)
Key facts
Ubiquitin carboxyl-terminal hydrolase 26 (USP26) is a protein from Homo sapiens identified by UniProt accession Q9BXU7, 913 residues long. MolForge cross-references it against 0 known binders and 183 disease associations.
- UniProt accession: Q9BXU7; gene symbol USP26.
- Organism: Homo sapiens.
- Length: 913 amino acids.
- Top disease associations (Open Targets): ovarian cancer, glioblastoma multiforme and breast adenocarcinoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Ubiquitin carboxyl-terminal hydrolase 26 |
|---|---|
| UniProt accession | Q9BXU7 |
| Gene | USP26 |
| Organism | Homo sapiens |
| Length | 913 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (183)
Diseases linked to this target (Open Targets).
- ovarian cancer · score 0.23
- glioblastoma multiforme · score 0.23
- breast adenocarcinoma · score 0.23
- esophageal cancer · score 0.10
- azoospermia · score 0.08
- primary ovarian insufficiency · score 0.07
- 46,XX gonadal dysgenesis · score 0.07
- male infertility · score 0.07
- Kallmann syndrome · score 0.07
- male infertility with teratozoospermia due to single gene mutation · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9BXU7-F1 | alphafold | PREDICTED | 59.96 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9BXU7.
Amino-acid sequence (913 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with USP26?
The strongest Open Targets associations for USP26 are ovarian cancer, glioblastoma multiforme, breast adenocarcinoma, esophageal cancer and azoospermia.
How long is the USP26 protein?
The Homo sapiens USP26 protein (UniProt Q9BXU7) is 913 amino acids long.
Browse: Targets: U · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9BXU7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9BXU7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.