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Ferritin heavy polypeptide-like 17 (FTHL17)

Homo sapiens — UniProt Q9BXU8

Gene: FTHL17Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Ferritin heavy polypeptide-like 17 (FTHL17) is a protein from Homo sapiens identified by UniProt accession Q9BXU8, 183 residues long. MolForge cross-references it against 0 known binders and 15 disease associations.

  • UniProt accession: Q9BXU8; gene symbol FTHL17.
  • Organism: Homo sapiens.
  • Length: 183 amino acids.
  • Top disease associations (Open Targets): cancer, calf circumference measurement and blood protein measurement.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameFerritin heavy polypeptide-like 17
UniProt accessionQ9BXU8
GeneFTHL17
OrganismHomo sapiens
Length183 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (15)

Diseases linked to this target (Open Targets).

  • cancer · score 0.04
  • calf circumference measurement · score 0.02
  • blood protein measurement · score 0.02
  • unipolar depression · score 0.02
  • Myocardial Ischemia · score 0.01
  • chronic kidney disease · score 0.00
  • breast cancer · score 0.00
  • lung adenocarcinoma · score 0.00
  • glioblastoma multiforme · score 0.00
  • neoplasm · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q9BXU8-F1alphafoldPREDICTED92.95—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9BXU8.

Amino-acid sequence (183 residues)

MATAQPSQVR QKYDTNCDAA INSHITLELY TSYLYLSMAF YFNRDDVALE NFFRYFLRLS DDKMEHAQKL MRLQNLRGGH ICLHDIRKPE CQGWESGLVA MESAFHLEKN VNQSLLDLYQ LAVEKGDPQL CHFLESHYLH EQVKTIKELG GYVSNLRKIC SPEAGLAEYL FDKLTLGGRV KET

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with FTHL17?

The strongest Open Targets associations for FTHL17 are cancer, calf circumference measurement, blood protein measurement, unipolar depression and Myocardial Ischemia.

How long is the FTHL17 protein?

The Homo sapiens FTHL17 protein (UniProt Q9BXU8) is 183 amino acids long.

Browse: Targets: F · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ9BXU8
GeneFTHL17
OrganismHomo sapiens
Length183
Binders0
Diseases15
View on UniProt