Calcium-binding protein 8 (CALN1)
Homo sapiens — UniProt Q9BXU9
Data last refreshed: (UniProt release unknown)
Key facts
Calcium-binding protein 8 (CALN1) is a protein from Homo sapiens identified by UniProt accession Q9BXU9, 261 residues long. MolForge cross-references it against 0 known binders and 52 disease associations.
- UniProt accession: Q9BXU9; gene symbol CALN1.
- Organism: Homo sapiens.
- Length: 261 amino acids.
- Top disease associations (Open Targets): self reported educational attainment, intelligence and body mass index.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Calcium-binding protein 8 |
|---|---|
| UniProt accession | Q9BXU9 |
| Gene | CALN1 |
| Organism | Homo sapiens |
| Length | 261 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (52)
Diseases linked to this target (Open Targets).
- self reported educational attainment · score 0.48
- intelligence · score 0.45
- body mass index · score 0.43
- schizophrenia · score 0.43
- cognitive function measurement · score 0.43
- mathematical ability · score 0.42
- body weight · score 0.39
- chronotype measurement · score 0.39
- attention deficit hyperactivity disorder · score 0.30
- verbal-numerical reasoning measurement · score 0.30
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9BXU9-F1 | alphafold | PREDICTED | 53.34 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9BXU9.
Amino-acid sequence (261 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CALN1?
The strongest Open Targets associations for CALN1 are self reported educational attainment, intelligence, body mass index, schizophrenia and cognitive function measurement.
How long is the CALN1 protein?
The Homo sapiens CALN1 protein (UniProt Q9BXU9) is 261 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9BXU9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9BXU9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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