EKC/KEOPS complex subunit GON7 (GON7)
Homo sapiens — UniProt Q9BXV9
Data last refreshed: (UniProt release unknown)
Key facts
EKC/KEOPS complex subunit GON7 (GON7) is a protein from Homo sapiens identified by UniProt accession Q9BXV9, 100 residues long. MolForge cross-references it against 0 known binders and 17 disease associations.
- UniProt accession: Q9BXV9; gene symbol GON7.
- Organism: Homo sapiens.
- Length: 100 amino acids.
- Top disease associations (Open Targets): Galloway-Mowat syndrome, Galloway-Mowat syndrome 9 and hip circumference.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | EKC/KEOPS complex subunit GON7 |
|---|---|
| UniProt accession | Q9BXV9 |
| Gene | GON7 |
| Organism | Homo sapiens |
| Length | 100 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (17)
Diseases linked to this target (Open Targets).
- Galloway-Mowat syndrome · score 0.59
- Galloway-Mowat syndrome 9 · score 0.51
- hip circumference · score 0.02
- mathematical ability · score 0.02
- Microcephaly · score 0.01
- cancer · score 0.01
- neoplasm · score 0.00
- nasopharyngeal neoplasm · score 0.00
- chronic kidney disease · score 0.00
- pancreatic ductal adenocarcinoma · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9BXV9-F1 | alphafold | PREDICTED | 76.09 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9BXV9.
Amino-acid sequence (100 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with GON7?
The strongest Open Targets associations for GON7 are Galloway-Mowat syndrome, Galloway-Mowat syndrome 9, hip circumference, mathematical ability and Microcephaly.
How long is the GON7 protein?
The Homo sapiens GON7 protein (UniProt Q9BXV9) is 100 amino acids long.
Browse: Targets: G · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9BXV9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9BXV9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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