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Microtubule-associated protein 1 light chain 3 gamma (MAP1LC3C)

Homo sapiens — UniProt Q9BXW4

Gene: MAP1LC3CHomo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Microtubule-associated protein 1 light chain 3 gamma (MAP1LC3C) is a protein from Homo sapiens identified by UniProt accession Q9BXW4, 147 residues long. MolForge cross-references it against 0 known binders and 36 disease associations.

  • UniProt accession: Q9BXW4; gene symbol MAP1LC3C.
  • Organism: Homo sapiens.
  • Length: 147 amino acids.
  • Top disease associations (Open Targets): breast adenocarcinoma, viral load and drug use measurement.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameMicrotubule-associated protein 1 light chain 3 gamma
UniProt accessionQ9BXW4
GeneMAP1LC3C
OrganismHomo sapiens
Length147 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (36)

Diseases linked to this target (Open Targets).

  • breast adenocarcinoma · score 0.18
  • viral load · score 0.05
  • drug use measurement · score 0.05
  • neoplasm · score 0.05
  • cancer · score 0.04
  • age at onset · score 0.04
  • Myopia · score 0.04
  • refractive error · score 0.03
  • PHF-tau measurement · score 0.02
  • neurofibrillary tangles measurement · score 0.02

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q9BXW4-F1alphafoldPREDICTED79.88—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9BXW4.

Amino-acid sequence (147 residues)

MPPPQKIPSV RPFKQRKSLA IRQEEVAGIR AKFPNKIPVV VERYPRETFL PPLDKTKFLV PQELTMTQFL SIIRSRMVLR ATEAFYLLVN NKSLVSMSAT MAEIYRDYKD EDGFVYMTYA SQETFGCLES AAPRDGSSLE DRPCNPL

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with MAP1LC3C?

The strongest Open Targets associations for MAP1LC3C are breast adenocarcinoma, viral load, drug use measurement, neoplasm and cancer.

How long is the MAP1LC3C protein?

The Homo sapiens MAP1LC3C protein (UniProt Q9BXW4) is 147 amino acids long.

Browse: Targets: M · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ9BXW4
GeneMAP1LC3C
OrganismHomo sapiens
Length147
Binders0
Diseases36
View on UniProt