Oxysterol-binding protein-related protein 1 (OSBPL1A)
Homo sapiens — UniProt Q9BXW6
Data last refreshed: (UniProt release unknown)
Key facts
Oxysterol-binding protein-related protein 1 (OSBPL1A) is a protein from Homo sapiens identified by UniProt accession Q9BXW6, 950 residues long. MolForge cross-references it against 0 known binders and 69 disease associations.
- UniProt accession: Q9BXW6; gene symbol OSBPL1A.
- Organism: Homo sapiens.
- Length: 950 amino acids.
- Top disease associations (Open Targets): neutrophil count, leukocyte count and myeloid white cell count.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Oxysterol-binding protein-related protein 1 |
|---|---|
| UniProt accession | Q9BXW6 |
| Gene | OSBPL1A |
| Organism | Homo sapiens |
| Length | 950 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (69)
Diseases linked to this target (Open Targets).
- neutrophil count · score 0.49
- leukocyte count · score 0.47
- myeloid white cell count · score 0.33
- protein measurement · score 0.32
- sex hormone-binding globulin measurement · score 0.21
- body fat percentage · score 0.14
- body mass index · score 0.13
- forced expiratory volume · score 0.13
- vital capacity · score 0.13
- cortical thickness · score 0.12
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9BXW6-F1 | alphafold | PREDICTED | 80.57 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9BXW6.
Amino-acid sequence (950 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with OSBPL1A?
The strongest Open Targets associations for OSBPL1A are neutrophil count, leukocyte count, myeloid white cell count, protein measurement and sex hormone-binding globulin measurement.
How long is the OSBPL1A protein?
The Homo sapiens OSBPL1A protein (UniProt Q9BXW6) is 950 amino acids long.
Browse: Targets: O · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9BXW6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9BXW6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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