Haloacid dehalogenase-like hydrolase domain-containing 5 (HDHD5)
Homo sapiens — UniProt Q9BXW7
Data last refreshed: (UniProt release unknown)
Key facts
Haloacid dehalogenase-like hydrolase domain-containing 5 (HDHD5) is a protein from Homo sapiens identified by UniProt accession Q9BXW7, 423 residues long. MolForge cross-references it against 0 known binders and 17 disease associations.
- UniProt accession: Q9BXW7; gene symbol HDHD5.
- Organism: Homo sapiens.
- Length: 423 amino acids.
- Top disease associations (Open Targets): lean body mass, body height and triglyceride measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Haloacid dehalogenase-like hydrolase domain-containing 5 |
|---|---|
| UniProt accession | Q9BXW7 |
| Gene | HDHD5 |
| Organism | Homo sapiens |
| Length | 423 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (17)
Diseases linked to this target (Open Targets).
- lean body mass · score 0.37
- body height · score 0.36
- triglyceride measurement · score 0.34
- fat body mass · score 0.33
- interleukin 17 receptor A measurement · score 0.31
- whole body water mass · score 0.26
- appendicular lean mass · score 0.26
- PHF-tau measurement · score 0.21
- non-alcoholic fatty liver disease severity measurement · score 0.14
- blood protein measurement · score 0.09
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9BXW7-F1 | alphafold | PREDICTED | 83.81 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9BXW7.
Amino-acid sequence (423 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with HDHD5?
The strongest Open Targets associations for HDHD5 are lean body mass, body height, triglyceride measurement, fat body mass and interleukin 17 receptor A measurement.
How long is the HDHD5 protein?
The Homo sapiens HDHD5 protein (UniProt Q9BXW7) is 423 amino acids long.
Browse: Targets: H · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9BXW7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9BXW7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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