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EMILIN-2 (EMILIN2)

Homo sapiens — UniProt Q9BXX0

Gene: EMILIN2Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

EMILIN-2 (EMILIN2) is a protein from Homo sapiens identified by UniProt accession Q9BXX0, 1053 residues long. MolForge cross-references it against 0 known binders and 110 disease associations.

  • UniProt accession: Q9BXX0; gene symbol EMILIN2.
  • Organism: Homo sapiens.
  • Length: 1053 amino acids.
  • Top disease associations (Open Targets): BMI-adjusted waist-hip ratio, sex hormone-binding globulin measurement and triglyceride measurement.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameEMILIN-2
UniProt accessionQ9BXX0
GeneEMILIN2
OrganismHomo sapiens
Length1053 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (110)

Diseases linked to this target (Open Targets).

  • BMI-adjusted waist-hip ratio · score 0.36
  • sex hormone-binding globulin measurement · score 0.30
  • triglyceride measurement · score 0.30
  • BMI-adjusted waist circumference · score 0.30
  • reticulocyte count · score 0.28
  • visual perception measurement · score 0.28
  • BMI-adjusted hip circumference · score 0.28
  • waist-hip ratio · score 0.27
  • refractive error measurement · score 0.25
  • body fat percentage · score 0.25

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q9BXX0-F1alphafoldPREDICTED65.10—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9BXX0.

Amino-acid sequence (1053 residues)

MWQPRRPWPR VPWRWALALL ALVGAGLCHA GPQPGYPARP SARNKNWCAY IVNKNVSCSV LEGSESFIQA QYNCAWNQMP CPSALVYRVN FRPRYVTRYK TVTQLEWRCC PGFRGGDCQE GPKDPVKTLR PTPARPRNSL KKATDNEPSQ FSEPRKTLSP TGTAQPSWGV DPKEGPQELQ EKKIQVLEEK VLRLTRTVLD LQSSLAGVSE NLKHATQDDA SRTRAPGLSS QHPKPDTTVS GDTETGQSPG VFNTKESGMK DIKSELAEVK DTLKNKSDKL EELDGKVKGY EGQLRQLQEA AQGPTVTMTT NELYQAYVDS KIDALREELM EGMDRKLADL KNSCEYKLTG LQQQCDDYGS SYLGVIELIG EKETSLRKEI NNLRARLQEP SAQANCCDSE KNGDIGQQIK TLDQKIERVA EATRMLNGRL DNEFDRLIVP EPDVDFDAKW NELDARINVT EKNAEEHCFY IEETLRGAIN GEVGDLKQLV DQKIQSLEDR LGSVLLQMTN NTGAELSPPG AAALPGVSGS GDERVMMELN HLKDKVQVVE DICLLNIQGK PHGMEGALPN REDRAVRDSL HLLKSLNDTM HRKFQETEQT IQKLQQDFSF LYSQLNHTEN DVTHLQKEMS NCRAGENAGM GRFTKVGEQE RTVDTLPSPQ HPVAHCCSQL EERWQRLQSQ VISELDACKE CTQGVQREVS MVEGRVSHME KTCSKLDSIS GNLQRIKEGL NKHVSSLWNC VRQMNGTLRS HSRDISGLKN SVQQFYSHVF QISTDLQDLV KFQPSAKAPS PPPPAEAPKE PLQPEPAPPR PSGPATAEDP GRRPVLPQRP PEERPPQPPG STGVIAETGQ AGPPAGAGVS GRGLPRGVDG QTGSGTVPGA EGFAGAPGYP KSPPVASPGA PVPSLVSFSA GLTQKPFPSD GGVVLFNKVL VNDGDVYNPS TGVFTAPYDG RYLITATLTP ERDAYVEAVL SVSNASVAQL HTAGYRREFL EYHRPPGALH TCGGPGAFHL IVHLKAGDAV NVVVTGGKLA HTDFDEMYST FSGVFLYPFL SHL

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with EMILIN2?

The strongest Open Targets associations for EMILIN2 are BMI-adjusted waist-hip ratio, sex hormone-binding globulin measurement, triglyceride measurement, BMI-adjusted waist circumference and reticulocyte count.

How long is the EMILIN2 protein?

The Homo sapiens EMILIN2 protein (UniProt Q9BXX0) is 1053 amino acids long.

Browse: Targets: E · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ9BXX0
GeneEMILIN2
OrganismHomo sapiens
Length1053
Binders0
Diseases110
View on UniProt