About Ankyrin repeat domain-containing protein 30B
Ankyrin repeat domain-containing protein 30B (ANKRD30B) is a protein
from Homo sapiens identified by UniProt accession
Q9BXX2, 1392 residues long.
MolForge cross-references it against 0 known binders and
14 disease associations.
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
Disease associations (14)
Diseases linked to this target (Open Targets).
- mean corpuscular volume · score 0.15
- arterial stiffness measurement · score 0.14
- reticulocyte count · score 0.13
- optic cup area measurement · score 0.12
- tooth agenesis · score 0.11
- central nervous system cancer · score 0.04
- Werner syndrome · score 0.02
- Myopia · score 0.02
- age at onset · score 0.02
- Williams syndrome · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
Experimental structures are not indexed in MolForge yet —
search RCSB PDB for Q9BXX2.
Amino-acid sequence (1392 residues)
MKRLLAAAGK GVRGPEPPNP FSERVYTEKD YGTIYFGDLG KIHTAASRGQ VQKLEKMTVG KKPVNLNKRD MKKRTALHWA CVNGHAEVVT FLVDRKCQLN VLDGEGRTPL MKALQCEREA CANILIDAGA DLNYVDVYGN TALHYAVYSE NLLMVATLLS YGAVIEVQNK ASLTPLLLAI QKRSKQTVEF LLTKNANANA FNESKCTALM LAICEGSSEI VGMLLQQNVD VFAEDIHGIT AERYAAACGV NYIHQQLLEH IRKLPKNPQN TNPEGTSTGT PDEAAPLAER TPDTAESLLE KTPDEAARLV EGTSAKIQCL GKATSGKFEQ STEETPRKIL RPTKETSEKF SWPAKERSRK ITWEEKETSV KTECVAGVTP NKTEVLEKGT SNMIACPTKE TSTKASTNVD VSSVEPIFSL FGTRTIENSQ CTKVEEDFNL ATKIISKSAA QNYTCLPDAT YQKDIKTINH KIEDQMFPSE SKREEDEEYS WDSGSLFESS AKTQVCIPES MYQKVMEINR EVEELPEKPS AFKPAVEMQK TVPNKAFELK NEQTLRAAQM FPSESKQKDD EENSWDSESP CETVSQKDVY LPKATHQKEF DTLSGKLEES PVKDGLLKPT CGRKVSLPNK ALELKDRETF KAESPDKDGL LKPTCGRKVS LPNKALELKD RETLKAESPD NDGLLKPTCG RKVSLPNKAL ELKDRETFKA AQMFPSESKQ KDDEENSWDF ESFLETLLQN DVCLPKATHQ KEFDTLSGKL EESPDKDGLL KPTCGMKISL PNKALELKDR ETFKAEDVSS VESTFSLFGK PTTENSQSTK VEEDFNLTTK EGATKTVTGQ QERDIGIIER APQDQTNKMP TSELGRKEDT KSTSDSEIIS VSDTQNYECL PEATYQKEIK TTNGKIEESP EKPSHFEPAT EMQNSVPNKG LEWKNKQTLR ADSTTLSKIL DALPSCERGR ELKKDNCEQI TAKMEQTKNK FCVLQKELSE AKEIKSQLEN QKAKWEQELC SVRLTLNQEE EKRRNVDILK EKIRPEEQLR KKLEVKQQLE QTLRIQDIEL KSVTSNLNQV SHTHESENDL FHENCMLKKE IAMLKLEVAT LKHQHQVKEN KYFEDIKILQ EKNAELQMTL KLKQKTVTKR ASQYREQLKV LTAENTMLTS KLKEKQDKEI LETEIESHHP RLASALQDHD QSVTSRKNQE LAFHSAGDAP LQGIMNVDVS NTIYNNEVLH QPLYEAQRKS KSPKINLNYA GDDLRENALV SEHAQRDRCE TQCQMKKAEH MYQNEQDNVD KHTEQQESLE QKLFQLESKN RWLRQQLVYA HKKVNKSKVT INIQFPEMKM QRHLNEKNEE VFNYGNHLKE RIDQYEKEKA EREVSIKKYK YFSNFLKESG LG
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