Ankyrin repeat domain-containing protein 30B (ANKRD30B)
Homo sapiens — UniProt Q9BXX2
Data last refreshed: (UniProt release unknown)
Key facts
Ankyrin repeat domain-containing protein 30B (ANKRD30B) is a protein from Homo sapiens identified by UniProt accession Q9BXX2, 1392 residues long. MolForge cross-references it against 0 known binders and 14 disease associations.
- UniProt accession: Q9BXX2; gene symbol ANKRD30B.
- Organism: Homo sapiens.
- Length: 1392 amino acids.
- Top disease associations (Open Targets): mean corpuscular volume, arterial stiffness measurement and reticulocyte count.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Ankyrin repeat domain-containing protein 30B |
|---|---|
| UniProt accession | Q9BXX2 |
| Gene | ANKRD30B |
| Organism | Homo sapiens |
| Length | 1392 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (14)
Diseases linked to this target (Open Targets).
- mean corpuscular volume · score 0.15
- arterial stiffness measurement · score 0.14
- reticulocyte count · score 0.13
- optic cup area measurement · score 0.12
- tooth agenesis · score 0.11
- central nervous system cancer · score 0.04
- Werner syndrome · score 0.02
- Myopia · score 0.02
- age at onset · score 0.02
- Williams syndrome · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9BXX2-F1 | alphafold | PREDICTED | 51.64 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9BXX2.
Amino-acid sequence (1392 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ANKRD30B?
The strongest Open Targets associations for ANKRD30B are mean corpuscular volume, arterial stiffness measurement, reticulocyte count, optic cup area measurement and tooth agenesis.
How long is the ANKRD30B protein?
The Homo sapiens ANKRD30B protein (UniProt Q9BXX2) is 1392 amino acids long.
Browse: Targets: A · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9BXX2 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9BXX2 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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