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Ankyrin repeat domain-containing protein 30A (ANKRD30A)

Homo sapiens — UniProt Q9BXX3

Gene: ANKRD30AHomo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Ankyrin repeat domain-containing protein 30A (ANKRD30A) is a protein from Homo sapiens identified by UniProt accession Q9BXX3, 1397 residues long. MolForge cross-references it against 0 known binders and 48 disease associations.

  • UniProt accession: Q9BXX3; gene symbol ANKRD30A.
  • Organism: Homo sapiens.
  • Length: 1397 amino acids.
  • Top disease associations (Open Targets): type 1 diabetes mellitus, ankylosing spondylitis and autoimmune thyroid disease.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameAnkyrin repeat domain-containing protein 30A
UniProt accessionQ9BXX3
GeneANKRD30A
OrganismHomo sapiens
Length1397 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (48)

Diseases linked to this target (Open Targets).

  • type 1 diabetes mellitus · score 0.31
  • ankylosing spondylitis · score 0.31
  • autoimmune thyroid disease · score 0.31
  • Crohn's disease · score 0.31
  • celiac disease · score 0.31
  • ulcerative colitis · score 0.31
  • autoimmune disease · score 0.31
  • juvenile idiopathic arthritis · score 0.31
  • psoriasis · score 0.31
  • systemic lupus erythematosus · score 0.31

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q9BXX3-F1alphafoldPREDICTED55.59—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9BXX3.

Amino-acid sequence (1397 residues)

MEEISAAAVK VVPGPERPSP FSQLVYTSND SYIVHSGDLR KIHKAASRGQ VRKLEKMTKR KKTINLNIQD AQKRTALHWA CVNGHEEVVT FLVDRKCQLD VLDGEHRTPL MKALQCHQEA CANILIDSGA DINLVDVYGN TALHYAVYSE ILSVVAKLLS HGAVIEVHNK ASLTPLLLSI TKRSEQIVEF LLIKNANANA VNKYKCTALM LAVCHGSSEI VGMLLQQNVD VFAADICGVT AEHYAVTCGF HHIHEQIMEY IRKLSKNHQN TNPEGTSAGT PDEAAPLAER TPDTAESLVE KTPDEAAPLV ERTPDTAESL VEKTPDEAAS LVEGTSDKIQ CLEKATSGKF EQSAEETPRE ITSPAKETSE KFTWPAKGRP RKIAWEKKED TPREIMSPAK ETSEKFTWAA KGRPRKIAWE KKETPVKTGC VARVTSNKTK VLEKGRSKMI ACPTKESSTK ASANDQRFPS ESKQEEDEEY SCDSRSLFES SAKIQVCIPE SIYQKVMEIN REVEEPPKKP SAFKPAIEMQ NSVPNKAFEL KNEQTLRADP MFPPESKQKD YEENSWDSES LCETVSQKDV CLPKATHQKE IDKINGKLEE SPNKDGLLKA TCGMKVSIPT KALELKDMQT FKAEPPGKPS AFEPATEMQK SVPNKALELK NEQTLRADEI LPSESKQKDY EENSWDTESL CETVSQKDVC LPKAAHQKEI DKINGKLEGS PVKDGLLKAN CGMKVSIPTK ALELMDMQTF KAEPPEKPSA FEPAIEMQKS VPNKALELKN EQTLRADEIL PSESKQKDYE ESSWDSESLC ETVSQKDVCL PKATHQKEID KINGKLEESP DNDGFLKAPC RMKVSIPTKA LELMDMQTFK AEPPEKPSAF EPAIEMQKSV PNKALELKNE QTLRADQMFP SESKQKKVEE NSWDSESLRE TVSQKDVCVP KATHQKEMDK ISGKLEDSTS LSKILDTVHS CERARELQKD HCEQRTGKME QMKKKFCVLK KKLSEAKEIK SQLENQKVKW EQELCSVRLT LNQEEEKRRN ADILNEKIRE ELGRIEEQHR KELEVKQQLE QALRIQDIEL KSVESNLNQV SHTHENENYL LHENCMLKKE IAMLKLEIAT LKHQYQEKEN KYFEDIKILK EKNAELQMTL KLKEESLTKR ASQYSGQLKV LIAENTMLTS KLKEKQDKEI LEAEIESHHP RLASAVQDHD QIVTSRKSQE PAFHIAGDAC LQRKMNVDVS STIYNNEVLH QPLSEAQRKS KSLKINLNYA GDALRENTLV SEHAQRDQRE TQCQMKEAEH MYQNEQDNVN KHTEQQESLD QKLFQLQSKN MWLQQQLVHA HKKADNKSKI TIDIHFLERK MQHHLLKEKN EEIFNYNNHL KNRIYQYEKE KAETENS

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with ANKRD30A?

The strongest Open Targets associations for ANKRD30A are type 1 diabetes mellitus, ankylosing spondylitis, autoimmune thyroid disease, Crohn's disease and celiac disease.

How long is the ANKRD30A protein?

The Homo sapiens ANKRD30A protein (UniProt Q9BXX3) is 1397 amino acids long.

Browse: Targets: A · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ9BXX3
GeneANKRD30A
OrganismHomo sapiens
Length1397
Binders0
Diseases48
View on UniProt