Large ribosomal subunit protein uL1m (MRPL1)
Homo sapiens — UniProt Q9BYD6
Data last refreshed: (UniProt release unknown)
Key facts
Large ribosomal subunit protein uL1m (MRPL1) is a protein from Homo sapiens identified by UniProt accession Q9BYD6, 325 residues long. MolForge cross-references it against 0 known binders and 20 disease associations.
- UniProt accession: Q9BYD6; gene symbol MRPL1.
- Organism: Homo sapiens.
- Length: 325 amino acids.
- Top disease associations (Open Targets): body fat percentage, lymphocyte count and brain volume measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Large ribosomal subunit protein uL1m |
|---|---|
| UniProt accession | Q9BYD6 |
| Gene | MRPL1 |
| Organism | Homo sapiens |
| Length | 325 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (20)
Diseases linked to this target (Open Targets).
- body fat percentage · score 0.26
- lymphocyte count · score 0.17
- brain volume measurement · score 0.12
- urate measurement · score 0.04
- bone density · score 0.04
- hemoglobin measurement · score 0.03
- rheumatoid arthritis · score 0.03
- C-X-C motif chemokine 10 measurement · score 0.02
- protein measurement · score 0.02
- DNA methylation · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9BYD6-F1 | alphafold | PREDICTED | 78.63 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9BYD6.
Amino-acid sequence (325 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with MRPL1?
The strongest Open Targets associations for MRPL1 are body fat percentage, lymphocyte count, brain volume measurement, urate measurement and bone density.
How long is the MRPL1 protein?
The Homo sapiens MRPL1 protein (UniProt Q9BYD6) is 325 amino acids long.
Browse: Targets: M · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9BYD6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9BYD6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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