Large ribosomal subunit protein uL1m (MRPL1)

About Large ribosomal subunit protein uL1m

Large ribosomal subunit protein uL1m (MRPL1) is a protein from Homo sapiens identified by UniProt accession Q9BYD6, 325 residues long. MolForge cross-references it against 0 known binders and 20 disease associations.

Target properties

Protein name	Large ribosomal subunit protein uL1m
UniProt accession	Q9BYD6
Gene	MRPL1
Organism	Homo sapiens
Length	325 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (20)

Diseases linked to this target (Open Targets).

body fat percentage · score 0.26
lymphocyte count · score 0.17
brain volume measurement · score 0.12
urate measurement · score 0.04
bone density · score 0.04
hemoglobin measurement · score 0.03
rheumatoid arthritis · score 0.03
C-X-C motif chemokine 10 measurement · score 0.02
protein measurement · score 0.02
DNA methylation · score 0.02

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9BYD6-F1	alphafold	PREDICTED	78.63	—

Amino-acid sequence (325 residues)

MAAAVRCMGR ALIHHQRHSL SKMVYQTSLC SCSVNIRVPN RHFAAATKSA KKTKKGAKEK TPDEKKDEIE KIKAYPYMEG EPEDDVYLKR LYPRQIYEVE KAVHLLKKFQ ILDFTSPKQS VYLDLTLDMA LGKKKNVEPF TSVLSLPYPF ASEINKVAVF TENASEVKIA EENGAAFAGG TSLIQKIWDD EIVADFYVAV PEIMPELNRL RKKLNKKYPK LSRNSIGRDI PKMLELFKNG HEIKVDEERE NFLQTKIATL DMSSDQIAAN LQAVINEVCR HRPLNLGPFV VRAFLRSSTS EGLLLKIDPL LPKEVKNEES EKEDA

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards