Hyccin (HYCC1)
Homo sapiens — UniProt Q9BYI3
Data last refreshed: (UniProt release unknown)
Key facts
Hyccin (HYCC1) is a protein from Homo sapiens identified by UniProt accession Q9BYI3, 521 residues long. MolForge cross-references it against 0 known binders and 74 disease associations.
- UniProt accession: Q9BYI3; gene symbol HYCC1.
- Organism: Homo sapiens.
- Length: 521 amino acids.
- Top disease associations (Open Targets): Hypomyelination - congenital cataract, hypomyelinating leukodystrophy 5 and adolescent idiopathic scoliosis.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Hyccin |
|---|---|
| UniProt accession | Q9BYI3 |
| Gene | HYCC1 |
| Organism | Homo sapiens |
| Length | 521 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (74)
Diseases linked to this target (Open Targets).
- Hypomyelination - congenital cataract · score 0.73
- hypomyelinating leukodystrophy 5 · score 0.53
- adolescent idiopathic scoliosis · score 0.31
- genetic disorder · score 0.19
- alcohol consumption measurement · score 0.13
- Thrombocytopenia · score 0.12
- alkaline phosphatase measurement · score 0.08
- pachyonychia congenita · score 0.05
- congenital dyserythropoietic anemia type 4 · score 0.04
- Congenital dyserythropoietic anemia type IV · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9BYI3-F1 | alphafold | PREDICTED | 67.74 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9BYI3.
Amino-acid sequence (521 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with HYCC1?
The strongest Open Targets associations for HYCC1 are Hypomyelination - congenital cataract, hypomyelinating leukodystrophy 5, adolescent idiopathic scoliosis, genetic disorder and alcohol consumption measurement.
How long is the HYCC1 protein?
The Homo sapiens HYCC1 protein (UniProt Q9BYI3) is 521 amino acids long.
Browse: Targets: H · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9BYI3 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9BYI3 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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