Keratin-associated protein 2-4 (KRTAP2-4)
Homo sapiens — UniProt Q9BYR9
Data last refreshed: (UniProt release unknown)
Key facts
Keratin-associated protein 2-4 (KRTAP2-4) is a protein from Homo sapiens identified by UniProt accession Q9BYR9, 128 residues long. MolForge cross-references it against 0 known binders and 5 disease associations.
- UniProt accession: Q9BYR9; gene symbol KRTAP2-4.
- Organism: Homo sapiens.
- Length: 128 amino acids.
- Top disease associations (Open Targets): arterial stiffness measurement, atopic eczema and psoriasis.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Keratin-associated protein 2-4 |
|---|---|
| UniProt accession | Q9BYR9 |
| Gene | KRTAP2-4 |
| Organism | Homo sapiens |
| Length | 128 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (5)
Diseases linked to this target (Open Targets).
- arterial stiffness measurement · score 0.18
- atopic eczema · score 0.00
- psoriasis · score 0.00
- neoplasm · score 0.00
- triple-negative breast cancer · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9BYR9-F1 | alphafold | PREDICTED | 33.67 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9BYR9.
Amino-acid sequence (128 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with KRTAP2-4?
The strongest Open Targets associations for KRTAP2-4 are arterial stiffness measurement, atopic eczema, psoriasis, neoplasm and triple-negative breast cancer.
How long is the KRTAP2-4 protein?
The Homo sapiens KRTAP2-4 protein (UniProt Q9BYR9) is 128 amino acids long.
Browse: Targets: K · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9BYR9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9BYR9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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