Anoctamin-3 (ANO3)
Homo sapiens — UniProt Q9BYT9
Data last refreshed: (UniProt release unknown)
Key facts
Anoctamin-3 (ANO3) is a protein from Homo sapiens identified by UniProt accession Q9BYT9, 981 residues long. MolForge cross-references it against 0 known binders and 99 disease associations.
- UniProt accession: Q9BYT9; gene symbol ANO3.
- Organism: Homo sapiens.
- Length: 981 amino acids.
- Top disease associations (Open Targets): Cranio-cervical dystonia with laryngeal and upper-limb involvement, Dystonia and dystonic disorder.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Anoctamin-3 |
|---|---|
| UniProt accession | Q9BYT9 |
| Gene | ANO3 |
| Organism | Homo sapiens |
| Length | 981 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (99)
Diseases linked to this target (Open Targets).
- Cranio-cervical dystonia with laryngeal and upper-limb involvement · score 0.71
- Dystonia · score 0.51
- dystonic disorder · score 0.50
- BMI-adjusted waist-hip ratio · score 0.49
- sex hormone-binding globulin measurement · score 0.45
- Febrile seizure (within the age range of 3 months to 6 years) · score 0.40
- COVID-19 · score 0.37
- HbA1c measurement · score 0.34
- genetic disorder · score 0.34
- waist-hip ratio · score 0.33
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9BYT9-F1 | alphafold | PREDICTED | 75.84 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9BYT9.
Amino-acid sequence (981 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ANO3?
The strongest Open Targets associations for ANO3 are Cranio-cervical dystonia with laryngeal and upper-limb involvement, Dystonia, dystonic disorder, BMI-adjusted waist-hip ratio and sex hormone-binding globulin measurement.
How long is the ANO3 protein?
The Homo sapiens ANO3 protein (UniProt Q9BYT9) is 981 amino acids long.
Browse: Targets: A · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9BYT9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9BYT9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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