Melanoma-associated antigen B5 (MAGEB5)
Homo sapiens — UniProt Q9BZ81
Data last refreshed: (UniProt release unknown)
Key facts
Melanoma-associated antigen B5 (MAGEB5) is a protein from Homo sapiens identified by UniProt accession Q9BZ81, 275 residues long. MolForge cross-references it against 0 known binders and 8 disease associations.
- UniProt accession: Q9BZ81; gene symbol MAGEB5.
- Organism: Homo sapiens.
- Length: 275 amino acids.
- Top disease associations (Open Targets): glioblastoma multiforme, carcinoma of liver and intrahepatic biliary tract and neoplasm.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Melanoma-associated antigen B5 |
|---|---|
| UniProt accession | Q9BZ81 |
| Gene | MAGEB5 |
| Organism | Homo sapiens |
| Length | 275 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (8)
Diseases linked to this target (Open Targets).
- glioblastoma multiforme · score 0.01
- carcinoma of liver and intrahepatic biliary tract · score 0.01
- neoplasm · score 0.01
- viral disease · score 0.01
- cancer · score 0.01
- benign prostatic hyperplasia · score 0.00
- calf circumference measurement · score 0.00
- male infertility · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9BZ81-F1 | alphafold | PREDICTED | 80.20 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9BZ81.
Amino-acid sequence (275 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with MAGEB5?
The strongest Open Targets associations for MAGEB5 are glioblastoma multiforme, carcinoma of liver and intrahepatic biliary tract, neoplasm, viral disease and cancer.
How long is the MAGEB5 protein?
The Homo sapiens MAGEB5 protein (UniProt Q9BZ81) is 275 amino acids long.
Browse: Targets: M · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9BZ81 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9BZ81 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.