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Protocadherin-11 X-linked (PCDH11X)

Homo sapiens — UniProt Q9BZA7

Gene: PCDH11XHomo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Protocadherin-11 X-linked (PCDH11X) is a protein from Homo sapiens identified by UniProt accession Q9BZA7, 1347 residues long. MolForge cross-references it against 0 known binders and 106 disease associations.

  • UniProt accession: Q9BZA7; gene symbol PCDH11X.
  • Organism: Homo sapiens.
  • Length: 1347 amino acids.
  • Top disease associations (Open Targets): tuberculosis, lung adenocarcinoma and anti-neutrophil antibody associated vasculitis.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameProtocadherin-11 X-linked
UniProt accessionQ9BZA7
GenePCDH11X
OrganismHomo sapiens
Length1347 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (106)

Diseases linked to this target (Open Targets).

  • tuberculosis · score 0.04
  • lung adenocarcinoma · score 0.03
  • anti-neutrophil antibody associated vasculitis · score 0.03
  • neoplasm · score 0.03
  • neuroblastoma · score 0.02
  • cancer · score 0.02
  • Autism · score 0.02
  • non-small cell lung carcinoma · score 0.01
  • Obesity · score 0.01
  • Rett syndrome · score 0.01

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q9BZA7-F1alphafoldPREDICTED63.95—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9BZA7.

Amino-acid sequence (1347 residues)

MDLLSGTYIF AVLLACVVFH SGAQEKNYTI REEMPENVLI GDLLKDLNLS LIPNKSLTTA MQFKLVYKTG DVPLIRIEED TGEIFTTGAR IDREKLCAGI PRDEHCFYEV EVAILPDEIF RLVKIRFLIE DINDNAPLFP ATVINISIPE NSAINSKYTL PAAVDPDVGI NGVQNYELIK SQNIFGLDVI ETPEGDKMPQ LIVQKELDRE EKDTYVMKVK VEDGGFPQRS STAILQVSVT DTNDNHPVFK ETEIEVSIPE NAPVGTSVTQ LHATDADIGE NAKIHFSFSN LVSNIARRLF HLNATTGLIT IKEPLDREET PNHKLLVLAS DGGLMPARAM VLVNVTDVND NVPSIDIRYI VNPVNDTVVL SENIPLNTKI ALITVTDKDA DHNGRVTCFT DHEIPFRLRP VFSNQFLLET AAYLDYESTK EYAIKLLAAD AGKPPLNQSA MLFIKVKDEN DNAPVFTQSF VTVSIPENNS PGIQLTKVSA MDADSGPNAK INYLLGPDAP PEFSLDCRTG MLTVVKKLDR EKEDKYLFTI LAKDNGVPPL TSNVTVFVSI IDQNDNSPVF THNEYNFYVP ENLPRHGTVG LITVTDPDYG DNSAVTLSIL DENDDFTIDS QTGVIRPNIS FDREKQESYT FYVKAEDGGR VSRSSSAKVT INVVDVNDNK PVFIVPPSNC SYELVLPSTN PGTVVFQVIA VDNDTGMNAE VRYSIVGGNT RDLFAIDQET GNITLMEKCD VTDLGLHRVL VKANDLGQPD SLFSVVIVNL FVNESVTNAT LINELVRKST EAPVTPNTEI ADVSSPTSDY VKILVAAVAG TITVVVVIFI TAVVRCRQAP HLKAAQKNKQ NSEWATPNPE NRQMIMMKKK KKKKKHSPKN LLLNFVTIEE TKADDVDSDG NRVTLDLPID LEEQTMGKYN WVTTPTTFKP DSPDLARHYK SASPQPAFQI QPETPLNSKH HIIQELPLDN TFVACDSISK CSSSSSDPYS VSDCGYPVTT FEVPVSVHTR PPMKEVVRSC TPMKESTTME IWIHPQPQRK SEGKVAGKSQ RRVTFHLPEG SQESSSDGGL GDHDAGSLTS TSHGLPLGYP QEEYFDRATP SNRTEGDGNS DPESTFIPGL KKAAEITVQP TVEEASDNCT QECLIYGHSD ACWMPASLDH SSSSQAQASA LCHSPPLSQA STQHHSPRVT QTIALCHSPP VTQTIALCHS PPPIQVSALH HSPPLVQATA LHHSPPSAQA SALCYSPPLA QAAAISHSSP LPQVIALHRS QAQSSVSLQQ GWVQGADGLC SVDQGVQGSA TSQFYTMSER LHPSDDSIKV IPLTTFTPRQ QARPSRGDSP IMEEHPL

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with PCDH11X?

The strongest Open Targets associations for PCDH11X are tuberculosis, lung adenocarcinoma, anti-neutrophil antibody associated vasculitis, neoplasm and neuroblastoma.

How long is the PCDH11X protein?

The Homo sapiens PCDH11X protein (UniProt Q9BZA7) is 1347 amino acids long.

Browse: Targets: P · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ9BZA7
GenePCDH11X
OrganismHomo sapiens
Length1347
Binders0
Diseases106
View on UniProt