BarH-like 1 homeobox protein (BARHL1)
Homo sapiens — UniProt Q9BZE3
Data last refreshed: (UniProt release unknown)
Key facts
BarH-like 1 homeobox protein (BARHL1) is a protein from Homo sapiens identified by UniProt accession Q9BZE3, 327 residues long. MolForge cross-references it against 0 known binders and 28 disease associations.
- UniProt accession: Q9BZE3; gene symbol BARHL1.
- Organism: Homo sapiens.
- Length: 327 amino acids.
- Top disease associations (Open Targets): neurofibrillary tangles measurement, Red cell distribution width and deafness.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | BarH-like 1 homeobox protein |
|---|---|
| UniProt accession | Q9BZE3 |
| Gene | BARHL1 |
| Organism | Homo sapiens |
| Length | 327 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (28)
Diseases linked to this target (Open Targets).
- neurofibrillary tangles measurement · score 0.09
- Red cell distribution width · score 0.07
- deafness · score 0.06
- Non-syndromic genetic deafness · score 0.05
- platelet count · score 0.04
- central nervous system cancer · score 0.04
- angiopoietin-1 receptor measurement · score 0.04
- Ataxia-telangiectasia · score 0.02
- drug use measurement · score 0.02
- neoplasm · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9BZE3-F1 | alphafold | PREDICTED | 65.36 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9BZE3.
Amino-acid sequence (327 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with BARHL1?
The strongest Open Targets associations for BARHL1 are neurofibrillary tangles measurement, Red cell distribution width, deafness, Non-syndromic genetic deafness and platelet count.
How long is the BARHL1 protein?
The Homo sapiens BARHL1 protein (UniProt Q9BZE3) is 327 amino acids long.
Browse: Targets: B · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9BZE3 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9BZE3 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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