WD repeat-containing protein 11 (WDR11)
Homo sapiens — UniProt Q9BZH6
Data last refreshed: (UniProt release unknown)
Key facts
WD repeat-containing protein 11 (WDR11) is a protein from Homo sapiens identified by UniProt accession Q9BZH6, 1224 residues long. MolForge cross-references it against 0 known binders and 248 disease associations.
- UniProt accession: Q9BZH6; gene symbol WDR11.
- Organism: Homo sapiens.
- Length: 1224 amino acids.
- Top disease associations (Open Targets): Microcephaly, isolated congenital hypogonadotropic hypogonadism and Kallmann syndrome.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | WD repeat-containing protein 11 |
|---|---|
| UniProt accession | Q9BZH6 |
| Gene | WDR11 |
| Organism | Homo sapiens |
| Length | 1224 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (248)
Diseases linked to this target (Open Targets).
- Microcephaly · score 0.59
- isolated congenital hypogonadotropic hypogonadism · score 0.57
- Kallmann syndrome · score 0.50
- Intellectual disability · score 0.42
- Short stature · score 0.42
- microcephaly · score 0.42
- hypogonadotropic hypogonadism · score 0.41
- prostate carcinoma · score 0.30
- benign prostatic hyperplasia · score 0.22
- lower urinary tract symptom · score 0.21
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9BZH6-F1 | alphafold | PREDICTED | 83.47 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9BZH6.
Amino-acid sequence (1224 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with WDR11?
The strongest Open Targets associations for WDR11 are Microcephaly, isolated congenital hypogonadotropic hypogonadism, Kallmann syndrome, Intellectual disability and Short stature.
How long is the WDR11 protein?
The Homo sapiens WDR11 protein (UniProt Q9BZH6) is 1224 amino acids long.
Browse: Targets: W · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9BZH6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9BZH6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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