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G-protein coupled receptor 62 (GPR62)

Homo sapiens — UniProt Q9BZJ7

Gene: GPR62Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

G-protein coupled receptor 62 (GPR62) is a protein from Homo sapiens identified by UniProt accession Q9BZJ7, 368 residues long. MolForge cross-references it against 0 known binders and 7 disease associations.

  • UniProt accession: Q9BZJ7; gene symbol GPR62.
  • Organism: Homo sapiens.
  • Length: 368 amino acids.
  • Top disease associations (Open Targets): reticulocyte count, Immature Reticulocyte Fraction Measurement and glioblastoma multiforme.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameG-protein coupled receptor 62
UniProt accessionQ9BZJ7
GeneGPR62
OrganismHomo sapiens
Length368 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (7)

Diseases linked to this target (Open Targets).

  • reticulocyte count · score 0.07
  • Immature Reticulocyte Fraction Measurement · score 0.02
  • glioblastoma multiforme · score 0.02
  • cancer · score 0.01
  • neoplasm · score 0.00
  • relapsing-remitting multiple sclerosis · score 0.00
  • myeloid sarcoma · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q9BZJ7-F1alphafoldPREDICTED76.55—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9BZJ7.

Amino-acid sequence (368 residues)

MANSTGLNAS EVAGSLGLIL AAVVEVGALL GNGALLVVVL RTPGLRDALY LAHLCVVDLL AAASIMPLGL LAAPPPGLGR VRLGPAPCRA ARFLSAALLP ACTLGVAALG LARYRLIVHP LRPGSRPPPV LVLTAVWAAA GLLGALSLLG TPPAPPPAPA RCSVLAGGLG PFRPLWALLA FALPALLLLG AYGGIFVVAR RAALRPPRPA RGSRLHSDSL DSRLSILPPL RPRLPGGKAA LAPALAVGQF AACWLPYGCA CLAPAARAAE AEAAVTWVAY SAFAAHPFLY GLLQRPVRLA LGRLSRRALP GPVRACTPQA WHPRALLQCL QRPPEGPAVG PSEAPEQTPE LAGGRSPAYQ GPPESSLS

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with GPR62?

The strongest Open Targets associations for GPR62 are reticulocyte count, Immature Reticulocyte Fraction Measurement, glioblastoma multiforme, cancer and neoplasm.

How long is the GPR62 protein?

The Homo sapiens GPR62 protein (UniProt Q9BZJ7) is 368 amino acids long.

Browse: Targets: G · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ9BZJ7
GeneGPR62
OrganismHomo sapiens
Length368
Binders0
Diseases7
View on UniProt