G-protein coupled receptor 61 (GPR61)
Homo sapiens — UniProt Q9BZJ8
Data last refreshed: (UniProt release unknown)
Key facts
G-protein coupled receptor 61 (GPR61) is a protein from Homo sapiens identified by UniProt accession Q9BZJ8, 451 residues long. MolForge cross-references it against 0 known binders and 78 disease associations.
- UniProt accession: Q9BZJ8; gene symbol GPR61.
- Organism: Homo sapiens.
- Length: 451 amino acids.
- Top disease associations (Open Targets): body mass index, lean body mass and body fat percentage.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | G-protein coupled receptor 61 |
|---|---|
| UniProt accession | Q9BZJ8 |
| Gene | GPR61 |
| Organism | Homo sapiens |
| Length | 451 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (78)
Diseases linked to this target (Open Targets).
- body mass index · score 0.30
- lean body mass · score 0.26
- body fat percentage · score 0.23
- fat body mass · score 0.21
- chronotype measurement · score 0.19
- hip circumference · score 0.19
- waist circumference · score 0.19
- physical activity measurement · score 0.18
- smoking behavior · score 0.16
- body weight · score 0.14
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9BZJ8-F1 | alphafold | PREDICTED | 69.26 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9BZJ8.
Amino-acid sequence (451 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with GPR61?
The strongest Open Targets associations for GPR61 are body mass index, lean body mass, body fat percentage, fat body mass and chronotype measurement.
How long is the GPR61 protein?
The Homo sapiens GPR61 protein (UniProt Q9BZJ8) is 451 amino acids long.
Browse: Targets: G · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9BZJ8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9BZJ8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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