Serine/threonine-protein kinase D2 (PRKD2)
Homo sapiens — UniProt Q9BZL6
Data last refreshed: (UniProt release unknown)
Key facts
Serine/threonine-protein kinase D2 (PRKD2) is a protein from Homo sapiens identified by UniProt accession Q9BZL6, 878 residues long. MolForge cross-references it against 15 known binders and 111 disease associations.
- UniProt accession: Q9BZL6; gene symbol PRKD2.
- Organism: Homo sapiens.
- Length: 878 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, multiple myeloma and heel bone mineral density.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Serine/threonine-protein kinase D2 |
|---|---|
| UniProt accession | Q9BZL6 |
| Gene | PRKD2 |
| Organism | Homo sapiens |
| Length | 878 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (111)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.49
- multiple myeloma · score 0.38
- heel bone mineral density · score 0.34
- aspartate aminotransferase measurement · score 0.31
- type 1 diabetes mellitus · score 0.30
- Parkinson disease · score 0.30
- Alzheimer disease · score 0.30
- lysosomal storage disease · score 0.30
- multiple sclerosis · score 0.30
- female reproductive system disease · score 0.26
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9BZL6-F1 | alphafold | PREDICTED | 68.62 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9BZL6.
Amino-acid sequence (878 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with PRKD2?
The strongest Open Targets associations for PRKD2 are neurodegenerative disease, multiple myeloma, heel bone mineral density, aspartate aminotransferase measurement and type 1 diabetes mellitus.
How long is the PRKD2 protein?
The Homo sapiens PRKD2 protein (UniProt Q9BZL6) is 878 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9BZL6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9BZL6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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