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UL16-binding protein 1 (ULBP1)

Homo sapiens — UniProt Q9BZM6

Gene: ULBP1Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

UL16-binding protein 1 (ULBP1) is a protein from Homo sapiens identified by UniProt accession Q9BZM6, 244 residues long. MolForge cross-references it against 0 known binders and 105 disease associations.

  • UniProt accession: Q9BZM6; gene symbol ULBP1.
  • Organism: Homo sapiens.
  • Length: 244 amino acids.
  • Top disease associations (Open Targets): neurodegenerative disease, platelet count and aspartate aminotransferase measurement.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameUL16-binding protein 1
UniProt accessionQ9BZM6
GeneULBP1
OrganismHomo sapiens
Length244 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (105)

Diseases linked to this target (Open Targets).

  • neurodegenerative disease · score 0.33
  • platelet count · score 0.30
  • aspartate aminotransferase measurement · score 0.30
  • blood protein measurement · score 0.24
  • hepatocellular carcinoma · score 0.09
  • neoplasm · score 0.09
  • infection · score 0.05
  • infect · score 0.05
  • pachyonychia congenita · score 0.03
  • Osteoporosis · score 0.03

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q9BZM6-F1alphafoldPREDICTED80.75—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9BZM6.

Amino-acid sequence (244 residues)

MAAAASPAFL LCLPLLHLLS GWSRAGWVDT HCLCYDFIIT PKSRPEPQWC EVQGLVDERP FLHYDCVNHK AKAFASLGKK VNVTKTWEEQ TETLRDVVDF LKGQLLDIQV ENLIPIEPLT LQARMSCEHE AHGHGRGSWQ FLFNGQKFLL FDSNNRKWTA LHPGAKKMTE KWEKNRDVTM FFQKISLGDC KMWLEEFLMY WEQMLDPTKP PSLAPGTTQP KAMATTLSPW SLLIIFLCFI LAGR

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with ULBP1?

The strongest Open Targets associations for ULBP1 are neurodegenerative disease, platelet count, aspartate aminotransferase measurement, blood protein measurement and hepatocellular carcinoma.

How long is the ULBP1 protein?

The Homo sapiens ULBP1 protein (UniProt Q9BZM6) is 244 amino acids long.

Browse: Targets: U · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ9BZM6
GeneULBP1
OrganismHomo sapiens
Length244
Binders0
Diseases105
View on UniProt