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UBX domain-containing protein 6 (UBXN6)

Homo sapiens — UniProt Q9BZV1

Gene: UBXN6Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

UBX domain-containing protein 6 (UBXN6) is a protein from Homo sapiens identified by UniProt accession Q9BZV1, 441 residues long. MolForge cross-references it against 0 known binders and 39 disease associations.

  • UniProt accession: Q9BZV1; gene symbol UBXN6.
  • Organism: Homo sapiens.
  • Length: 441 amino acids.
  • Top disease associations (Open Targets): neurodegenerative disease, mean corpuscular volume and mean corpuscular hemoglobin concentration.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameUBX domain-containing protein 6
UniProt accessionQ9BZV1
GeneUBXN6
OrganismHomo sapiens
Length441 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (39)

Diseases linked to this target (Open Targets).

  • neurodegenerative disease · score 0.37
  • mean corpuscular volume · score 0.29
  • mean corpuscular hemoglobin concentration · score 0.23
  • mean corpuscular hemoglobin · score 0.20
  • appendicular lean mass · score 0.20
  • mean reticulocyte volume · score 0.20
  • Red cell distribution width · score 0.15
  • lean body mass · score 0.14
  • female infertility · score 0.14
  • hemoglobin measurement · score 0.12

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q9BZV1-F1alphafoldPREDICTED75.98—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9BZV1.

Amino-acid sequence (441 residues)

MKKFFQEFKA DIKFKSAGPG QKLKESVGEK AHKEKPNQPA PRPPRQGPTN EAQMAAAAAL ARLEQKQSRA WGPTSQDTIR NQVRKELQAE ATVSGSPEAP GTNVVSEPRE EGSAHLAVPG VYFTCPLTGA TLRKDQRDAC IKEAILLHFS TDPVAASIMK IYTFNKDQDR VKLGVDTIAK YLDNIHLHPE EEKYRKIKLQ NKVFQERINC LEGTHEFFEA IGFQKVLLPA QDQEDPEEFY VLSETTLAQP QSLERHKEQL LAAEPVRAKL DRQRRVFQPS PLASQFELPG DFFNLTAEEI KREQRLRSEA VERLSVLRTK AMREKEEQRG LRKYNYTLLR VRLPDGCLLQ GTFYARERLG AVYGFVREAL QSDWLPFELL ASGGQKLSED ENLALNECGL VPSALLTFSW DMAVLEDIKA AGAEPDSILK PELLSAIEKL L

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with UBXN6?

The strongest Open Targets associations for UBXN6 are neurodegenerative disease, mean corpuscular volume, mean corpuscular hemoglobin concentration, mean corpuscular hemoglobin and appendicular lean mass.

How long is the UBXN6 protein?

The Homo sapiens UBXN6 protein (UniProt Q9BZV1) is 441 amino acids long.

Browse: Targets: U · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ9BZV1
GeneUBXN6
OrganismHomo sapiens
Length441
Binders0
Diseases39
View on UniProt