Contactin-associated protein-like 4 (CNTNAP4)
Homo sapiens — UniProt Q9C0A0
Data last refreshed: (UniProt release unknown)
Key facts
Contactin-associated protein-like 4 (CNTNAP4) is a protein from Homo sapiens identified by UniProt accession Q9C0A0, 1308 residues long. MolForge cross-references it against 0 known binders and 58 disease associations.
- UniProt accession: Q9C0A0; gene symbol CNTNAP4.
- Organism: Homo sapiens.
- Length: 1308 amino acids.
- Top disease associations (Open Targets): mathematical ability, cognitive function measurement and self reported educational attainment.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Contactin-associated protein-like 4 |
|---|---|
| UniProt accession | Q9C0A0 |
| Gene | CNTNAP4 |
| Organism | Homo sapiens |
| Length | 1308 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (58)
Diseases linked to this target (Open Targets).
- mathematical ability · score 0.43
- cognitive function measurement · score 0.40
- self reported educational attainment · score 0.39
- 3-hydroxy-1-methylpropylmercapturic acid measurement · score 0.32
- smoking status measurement · score 0.31
- smoking behavior · score 0.31
- sphingolipid measurement · score 0.30
- fat body mass · score 0.18
- body fat percentage · score 0.15
- arterial stiffness measurement · score 0.13
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9C0A0-F1 | alphafold | PREDICTED | 83.40 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9C0A0.
Amino-acid sequence (1308 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CNTNAP4?
The strongest Open Targets associations for CNTNAP4 are mathematical ability, cognitive function measurement, self reported educational attainment, 3-hydroxy-1-methylpropylmercapturic acid measurement and smoking status measurement.
How long is the CNTNAP4 protein?
The Homo sapiens CNTNAP4 protein (UniProt Q9C0A0) is 1308 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9C0A0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9C0A0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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