BMP/retinoic acid-inducible neural-specific protein 2 (BRINP2)
Homo sapiens — UniProt Q9C0B6
Data last refreshed: (UniProt release unknown)
Key facts
BMP/retinoic acid-inducible neural-specific protein 2 (BRINP2) is a protein from Homo sapiens identified by UniProt accession Q9C0B6, 783 residues long. MolForge cross-references it against 0 known binders and 58 disease associations.
- UniProt accession: Q9C0B6; gene symbol BRINP2.
- Organism: Homo sapiens.
- Length: 783 amino acids.
- Top disease associations (Open Targets): schizophrenia, autism spectrum disorder and diet measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | BMP/retinoic acid-inducible neural-specific protein 2 |
|---|---|
| UniProt accession | Q9C0B6 |
| Gene | BRINP2 |
| Organism | Homo sapiens |
| Length | 783 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (58)
Diseases linked to this target (Open Targets).
- schizophrenia · score 0.45
- autism spectrum disorder · score 0.33
- diet measurement · score 0.28
- unipolar depression · score 0.27
- bipolar disorder · score 0.17
- adolescent idiopathic scoliosis · score 0.17
- mathematical ability · score 0.16
- attention deficit hyperactivity disorder · score 0.15
- coffee consumption · score 0.14
- protein measurement · score 0.14
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9C0B6-F1 | alphafold | PREDICTED | 75.96 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9C0B6.
Amino-acid sequence (783 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with BRINP2?
The strongest Open Targets associations for BRINP2 are schizophrenia, autism spectrum disorder, diet measurement, unipolar depression and bipolar disorder.
How long is the BRINP2 protein?
The Homo sapiens BRINP2 protein (UniProt Q9C0B6) is 783 amino acids long.
Browse: Targets: B · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9C0B6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9C0B6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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