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Zinc finger CCHC domain-containing protein 2 (ZCCHC2)

Homo sapiens — UniProt Q9C0B9

Gene: ZCCHC2Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Zinc finger CCHC domain-containing protein 2 (ZCCHC2) is a protein from Homo sapiens identified by UniProt accession Q9C0B9, 1178 residues long. MolForge cross-references it against 0 known binders and 79 disease associations.

  • UniProt accession: Q9C0B9; gene symbol ZCCHC2.
  • Organism: Homo sapiens.
  • Length: 1178 amino acids.
  • Top disease associations (Open Targets): serum albumin measurement, chronotype measurement and neutrophil count.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameZinc finger CCHC domain-containing protein 2
UniProt accessionQ9C0B9
GeneZCCHC2
OrganismHomo sapiens
Length1178 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (79)

Diseases linked to this target (Open Targets).

  • serum albumin measurement · score 0.48
  • chronotype measurement · score 0.46
  • neutrophil count · score 0.46
  • calcium measurement · score 0.46
  • C-reactive protein measurement · score 0.45
  • leukocyte count · score 0.43
  • stressful life event measurement · score 0.43
  • depressive symptom measurement · score 0.43
  • self reported educational attainment · score 0.41
  • pulse pressure measurement · score 0.41

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q9C0B9-F1alphafoldPREDICTED48.99—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9C0B9.

Amino-acid sequence (1178 residues)

MLRMKLPLKP THPAEPPPEA EEPEADARPG AKAPSRRRRD CRPPPPPPPP AGPSRGPLPP PPPPRGLGPP VAGGAAAGAG MPGGGGGPSA ALREQERVYE WFGLVLGSAQ RLEFMCGLLD LCNPLELRFL GSCLEDLARK DYHYLRDSEA KANGLSDPGP LADFREPAVR SRLIVYLALL GSENREAAGR LHRLLPQVDS VLKSLRAARG EGSRGGAEDE RGEDGDGEQD AEKDGSGPEG GIVEPRVGGG LGSRAQEELL LLFTMASLHP AFSFHQRVTL REHLERLRAA LRGGPEDAEV EVEPCKFAGP RAQNNSAHGD YMQNNESSLI EQAPIPQDGL TVAPHRAQRE AVHIEKIMLK GVQRKRADKY WEYTFKVNWS DLSVTTVTKT HQELQEFLLK LPKELSSETF DKTILRALNQ GSLKREERRH PDLEPILRQL FSSSSQAFLQ SQKVHSFFQS ISSDSLHSIN NLQSSLKTSK ILEHLKEDSS EASSQEEDVL QHAIIHKKHT GKSPIVNNIG TSCSPLDGLT MQYSEQNGIV DWRKQSCTTI QHPEHCVTSA DQHSAEKRSL SSINKKKGKP QTEKEKIKKT DNRLNSRING IRLSTPQHAH GGTVKDVNLD IGSGHDTCGE TSSESYSSPS SPRHDGRESF ESEEEKDRDT DSNSEDSGNP STTRFTGYGS VNQTVTVKPP VQIASLGNEN GNLLEDPLNS PKYQHISFMP TLHCVMHNGA QKSEVVVPAP KPADGKTIGM LVPSPVAISA IRESANSTPV GILGPTACTG ESEKHLELLA SPLPIPSTFL PHSSTPALHL TVQRLKLPPP QGSSESCTVN IPQQPPGSLS IASPNTAFIP IHNPGSFPGS PVATTDPITK SASQVVGLNQ MVPQIEGNTG TVPQPTNVKV VLPAAGLSAA QPPASYPLPG SPLAAGVLPS QNSSVLSTAA TSPQPASAGI SQAQATVPPA VPTHTPGPAP SPSPALTHST AQSDSTSYIS AVGNTNANGT VVPPQQMGSG PCGSCGRRCS CGTNGNLQLN SYYYPNPMPG PMYRVPSFFT LPSICNGSYL NQAHQSNGNQ LPFFLPQTPY ANGLVHDPVM GSQANYGMQQ MAGFGRFYPV YPAPNVVANT SGSGPKKNGN VSCYNCGVSG HYAQDCKQSS MEANQQGTYR LRYAPPLPPS NDTLDSAD

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with ZCCHC2?

The strongest Open Targets associations for ZCCHC2 are serum albumin measurement, chronotype measurement, neutrophil count, calcium measurement and C-reactive protein measurement.

How long is the ZCCHC2 protein?

The Homo sapiens ZCCHC2 protein (UniProt Q9C0B9) is 1178 amino acids long.

Browse: Targets: Z · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ9C0B9
GeneZCCHC2
OrganismHomo sapiens
Length1178
Binders0
Diseases79
View on UniProt