FH2 domain-containing protein 1 (FHDC1)
Homo sapiens — UniProt Q9C0D6
Data last refreshed: (UniProt release unknown)
Key facts
FH2 domain-containing protein 1 (FHDC1) is a protein from Homo sapiens identified by UniProt accession Q9C0D6, 1143 residues long. MolForge cross-references it against 0 known binders and 35 disease associations.
- UniProt accession: Q9C0D6; gene symbol FHDC1.
- Organism: Homo sapiens.
- Length: 1143 amino acids.
- Top disease associations (Open Targets): reticulocyte count, Red cell distribution width and reticulocyte measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | FH2 domain-containing protein 1 |
|---|---|
| UniProt accession | Q9C0D6 |
| Gene | FHDC1 |
| Organism | Homo sapiens |
| Length | 1143 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (35)
Diseases linked to this target (Open Targets).
- reticulocyte count · score 0.31
- Red cell distribution width · score 0.30
- reticulocyte measurement · score 0.30
- Immature Reticulocyte Fraction Measurement · score 0.26
- mean corpuscular hemoglobin concentration · score 0.19
- FEV/FVC ratio · score 0.16
- mean platelet volume · score 0.16
- lower respiratory tract disease · score 0.11
- psychotic symptoms · score 0.09
- HbA1c measurement · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9C0D6-F1 | alphafold | PREDICTED | 57.53 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9C0D6.
Amino-acid sequence (1143 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with FHDC1?
The strongest Open Targets associations for FHDC1 are reticulocyte count, Red cell distribution width, reticulocyte measurement, Immature Reticulocyte Fraction Measurement and mean corpuscular hemoglobin concentration.
How long is the FHDC1 protein?
The Homo sapiens FHDC1 protein (UniProt Q9C0D6) is 1143 amino acids long.
Browse: Targets: F · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9C0D6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9C0D6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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