Glutamate receptor-interacting protein 2 (GRIP2)
Homo sapiens — UniProt Q9C0E4
Data last refreshed: (UniProt release unknown)
Key facts
Glutamate receptor-interacting protein 2 (GRIP2) is a protein from Homo sapiens identified by UniProt accession Q9C0E4, 1043 residues long. MolForge cross-references it against 0 known binders and 15 disease associations.
- UniProt accession: Q9C0E4; gene symbol GRIP2.
- Organism: Homo sapiens.
- Length: 1043 amino acids.
- Top disease associations (Open Targets): gut microbiome measurement, adolescent idiopathic scoliosis and gastric carcinoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Glutamate receptor-interacting protein 2 |
|---|---|
| UniProt accession | Q9C0E4 |
| Gene | GRIP2 |
| Organism | Homo sapiens |
| Length | 1043 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (15)
Diseases linked to this target (Open Targets).
- gut microbiome measurement · score 0.31
- adolescent idiopathic scoliosis · score 0.27
- gastric carcinoma · score 0.03
- lymphocyte percentage of leukocytes · score 0.03
- PHF-tau measurement · score 0.03
- hepatocellular carcinoma · score 0.01
- oral squamous cell carcinoma · score 0.01
- neoplasm · score 0.00
- systemic lupus erythematosus · score 0.00
- prostate adenocarcinoma · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9C0E4-F1 | alphafold | PREDICTED | 62.65 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9C0E4.
Amino-acid sequence (1043 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with GRIP2?
The strongest Open Targets associations for GRIP2 are gut microbiome measurement, adolescent idiopathic scoliosis, gastric carcinoma, lymphocyte percentage of leukocytes and PHF-tau measurement.
How long is the GRIP2 protein?
The Homo sapiens GRIP2 protein (UniProt Q9C0E4) is 1043 amino acids long.
Browse: Targets: G · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9C0E4 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9C0E4 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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