Zinc finger protein 407 (ZNF407)

Homo sapiens — UniProt Q9C0G0

Gene: ZNF407Homo sapiensSwissProt reviewed

Data last refreshed: 2026-04-18 (UniProt release unknown)

Key facts

Zinc finger protein 407 (ZNF407) is a protein from Homo sapiens identified by UniProt accession Q9C0G0, 2248 residues long. MolForge cross-references it against 0 known binders and 54 disease associations.

UniProt accession: Q9C0G0; gene symbol ZNF407.
Organism: Homo sapiens.
Length: 2248 amino acids.
Top disease associations (Open Targets): Red cell distribution width, Neurodevelopmental delay and mean reticulocyte volume.
3D structure: AlphaFold model available.

Target properties

Protein name	Zinc finger protein 407
UniProt accession	Q9C0G0
Gene	ZNF407
Organism	Homo sapiens
Length	2248 residues
Molecular weight	—
EC numbers	—
Target class	—
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (54)

Diseases linked to this target (Open Targets).

Red cell distribution width · score 0.34
Neurodevelopmental delay · score 0.33
mean reticulocyte volume · score 0.22
smoking status measurement · score 0.20
Intellectual disability · score 0.19
Global developmental delay · score 0.18
attention deficit hyperactivity disorder · score 0.18
hematocrit · score 0.18
hypertension · score 0.18
mean corpuscular volume · score 0.17

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9C0G0-F1	alphafold	PREDICTED	45.66	—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9C0G0.

Amino-acid sequence (2248 residues)

MMDSENKPEN DEDEKINKEA QDLTKLSSHN EDGGPVSDVI ASFPENSMGK RGFSESSNSD SVVIGEDRNK HASKRRKLDE AEPLKSGKQG ICRLETSESS VTEGGIALDE TGKETFLSDC TVGGTCLPNA LSPSCNFSTI DVVSLKTDTE KTSAQEMVSL DLERESPFPP KEISVSCTIG NVDTVLKCSI CGHLFSSCSD LEKHAESHMQ QPKEHTCCHC SHKAESSSAL HMHIKQAHGP QKVFSCDLCG FQCSEENLLN AHYLGKTHLR RQNLAARGGF VQILTKQPFP KKSRTMATKN VHSKPRTSKS IAKNSDSKGL RNVGSTFKDF RGSISKQSGS SSELLVEMMP SRNTLSQEVE IVEEHVTSLG LAQNPENQSR KLDTLVTSEG LLEKLESTKN TLQAAHGNSV TSRPRPERNI LVLGNSFRRR SSTFTLKGQA KKRFNLLGIK RGTSETQRMY MKHLRTQMKT HDAESVLKHL EACSSVQRVC VTTSETQEAE QGQGSARPPD SGLHSLTVKP ASGSQTLCAC TDCGQVATNR TDLEIHVKRC HAREMKFYCR TCDFSSMSRR DLDEHLHSNQ HQQTASVLSC QCCSFISLDE INLRDHMKEK HNMHFLCTPC NLFFLSEKDV EEHKATEKHI NSLVQPKTLQ SSNSDLVLQT LPLSTLESEN AKESMDDSGK ASQEEPLKSR VSHGNEVRHS SKPQFQCKKC FYKTRSSTVL TRHIKLRHGQ DYHFLCKACN LYSLSKEGME KHIKRSKHLE NAKKNNIGLS FEECIERVCI GANDKKEEFD VSGNGRIEGH IGVQLQEHSY LEKGMLASEE LSQSGGSTKD DELASTTTPK RGRPKGNISR TCSHCGLLAS SITNLTVHIR RKHSHQYSYL CKVCKYYTVT KGDMERHCAT KKHKGRVEIE ASGKHSSDII VGPEGGSLEA GKKNAGSAVT MSDEHANKPA ESPTSVLEKP DRGNSIEAEV ENVFHSLDGE VNSHLLDKKE QISSEPEDFA QPGDVYSQRD VTGTGENKCL HCEFSAHSSA SLELHVKRKH TKEFEFYCMA CDYYAVTRRE MTRHAATEKH KMKRQSYLNS ANVEAGSADM SKNIIMPEEE HQQNSEEFQI ISGQPSDTLK SRNAADCSIL NENTNLDMSK VLCAADSVEV ETEEESNFNE DHSFCETFQQ APVKDKVRKP EEMMSLTMSS NYGSPSRFQN ENSGSSALNC ETAKKNHEIS NDAGELRVHC EGEGGNAGDG GGVVPHRHLC PVTLDGERSA ESPVLVVTRI TREQGNLESG GQNRVARGHG LEDLKGVQED PVLGNKEILM NSQHETEFIL EEDGPASDST VESSDVYETI ISIDDKGQAM YSFGRFDSSI IRIKNPEDGE LIDQSEEGLI ATGVRISELP LKDCAQGVKK KKSEGSSIGE STRIRCDDCG FLADGLSGLN VHIAMKHPTK EKHFHCLLCG KSFYTESNLH QHLASAGHMR NEQASVEELP EGGATFKCVK CTEPFDSEQN LFLHIKGQHE ELLREVNKYI VEDTEQINRE REENQGNVCK YCGKMCRSSN SMAFLAHIRT HTGSKPFKCK ICHFATAQLG DARNHVKRHL GMREYKCHVC GVAFVMKKHL NTHLLGKHGV GTPKERKFTC HLCDRSFTEK WALNNHMKLH TGEKPFKCTW PTCHYSFLTA SAMKDHYRTH TGEKSFLCDL CGFAGGTRHA LTKHRRQHTG EKPFKCDECN FASTTQSHLT RHKRVHTGEK PYRCPWCDYR SNCAENIRKH ILHTGKHEGV KMYNCPKCDY GTNVPVEFRN HLKEQHPDIE NPDLAYLHAG IVSKSYECRL KGQGATFVET DSPFTAAALA EEPLVKEKPL RSSRRPAPPP EQVQQVIIFQ GYDGEFALDP SVEETAAATL QTLAMAGQVA RVVHITEDGQ VIATSQSGAH VGSVVPGPIL PEQLADGATQ VVVVGGSMEG HGMDESLSPG GAVIQQVTKQ EILNLSEAGV APPEASSALD ALLCAVTELG EVEGRAGLEE QGRPGAKDVL IQLPGQEVSH VAADPEAPEI QMFPQAQESP AAVEVLTQVV HPSAAMASQE RAQVAFKKMV QGVLQFAVCD TAAAGQLVKD GVTQVVVSEE GAVHMVAGEG AQIIMQEAQG EHMDLVESDG EISQIIVTEE LVQAMVQESS GGFSEGTTHY ILTELPPGVQ DEPGLYSHTV LETADSQELL QAGATLGTEA GAPSRAEQLA SVVIYTQEGS SAAAAIQSQR ESSELQEA

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with ZNF407?

The strongest Open Targets associations for ZNF407 are Red cell distribution width, Neurodevelopmental delay, mean reticulocyte volume, smoking status measurement and Intellectual disability.

How long is the ZNF407 protein?

The Homo sapiens ZNF407 protein (UniProt Q9C0G0) is 2248 amino acids long.

Browse: Targets: Z · all protein targets A–Z · drugs A–Z.

Sources

UniProtKB Q9C0G0 — name, gene, function, sequence, keywords (CC BY 4.0)
AlphaFold DB Q9C0G0 — predicted 3D structure (CC BY 4.0)
Open Targets Platform — disease associations and tractability (CC0)

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.