SRC kinase signaling inhibitor 1 (SRCIN1)
Homo sapiens — UniProt Q9C0H9
Data last refreshed: (UniProt release unknown)
Key facts
SRC kinase signaling inhibitor 1 (SRCIN1) is a protein from Homo sapiens identified by UniProt accession Q9C0H9, 1183 residues long. MolForge cross-references it against 0 known binders and 56 disease associations.
- UniProt accession: Q9C0H9; gene symbol SRCIN1.
- Organism: Homo sapiens.
- Length: 1183 amino acids.
- Top disease associations (Open Targets): neoplasm, non-small cell lung carcinoma and breast cancer.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | SRC kinase signaling inhibitor 1 |
|---|---|
| UniProt accession | Q9C0H9 |
| Gene | SRCIN1 |
| Organism | Homo sapiens |
| Length | 1183 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (56)
Diseases linked to this target (Open Targets).
- neoplasm · score 0.11
- non-small cell lung carcinoma · score 0.11
- breast cancer · score 0.09
- cancer · score 0.06
- colon carcinoma · score 0.06
- platelet count · score 0.05
- hypertension · score 0.05
- neuroblastoma · score 0.04
- nervous system disease · score 0.03
- glioblastoma multiforme · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9C0H9-F1 | alphafold | PREDICTED | 53.86 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9C0H9.
Amino-acid sequence (1183 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SRCIN1?
The strongest Open Targets associations for SRCIN1 are neoplasm, non-small cell lung carcinoma, breast cancer, cancer and colon carcinoma.
How long is the SRCIN1 protein?
The Homo sapiens SRCIN1 protein (UniProt Q9C0H9) is 1183 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9C0H9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9C0H9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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